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A distal super enhancer mediates estrogen-dependent mouse uterine-specific gene transcription of Igf1 (insulin-like growth factor 1)

Hewitt, SC; Lierz, SL; Garcia, M; Hamilton, KJ; Gruzdev, A; Grimm, SA; Lydon, JP; Demayo, FJ; Korach, KS

Hewitt, SC (reprint author), NIEHS, Receptor Biol Grp, NIH, POB 12233, Res Triangle Pk, NC 27709 USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2019; 294 (25): 9746

Abstract

Insulin-like growth factor 1 (IGF1) is primarily synthesized in and secreted from the liver; however, estrogen (E2), through E2 receptor (ER), increas......

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