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Synthesis and analysis of isotopically stable labeled nitrosamines as mass spectrometry standards for drug impurity quality control

Derdau, V; Sandvoss, M

Derdau, V (通讯作者),Sanofi Germany, R&D, Integrated Drug Discovery, Isotope Chem,Industriepk Hochst, D-65926 Frankfurt, Germany.

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2023; 66 (2): 41

Abstract

We describe a simple and easy pathway to synthesize nitrosamine mass spectrometry standards in good to moderate yields. N-alkylation of Boc-protected ......

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