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Human Hyaluronidase PH20 Potentiates the Antitumor Activities of Mesothelin-Specific CAR-T Cells Against Gastric Cancer

Zhao, RC; Cui, YB; Zheng, YF; Li, SL; Lv, J; Wu, QT; Long, YG; Wang, SN; Yao, Y; Wei, W; Yang, J; Wang, BC; Zhang, ZF; Zeng, H; Li, YQ; Li, P

Li, YQ (corresponding author), Jinan Univ, Affiliated Hosp 1, Dept Hematol, Guangzhou, Guangdong, Peoples R China.; Li, P (corresponding author), Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Ctr Cell Regenerat & Biotherapy, Guangzhou, Guangdong, Peoples R China.; Li, P (corresponding author), Univ Chinese Acad Sci, Beijing, Peoples R China.; Li, YQ (corresponding author), Jinan Univ, Sch Med, Inst Hematol, Key Lab Regenerat Med,Minist Educ, Guangzhou, Guangdong, Peoples R China.; Li, P (corre

FRONTIERS IN IMMUNOLOGY, 2021; 12 ():

Abstract

T cell infiltration into tumors is essential for successful immunotherapy against solid tumors. Herein, we found that the expression of hyaluronic aci......

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