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Induction of the apoptosis, degranulation and IL-13 production of human basophils by butyrate and propionate via suppression of histone deacetylation

Shi, YB; Xu, MZ; Pan, S; Gao, SJ; Ren, JF; Bai, RX; Li, H; He, C; Zhao, SL; Shi, ZX; Yu, F; Xiang, Z; Wang, H

Wang, H (corresponding author), Xuzhou Med Univ, Dept Pathogen Biol & Immunol, 209 Tongshan Rd, Xuzhou 221004, Jiangsu, Peoples R China.

IMMUNOLOGY, 2021; 164 (2): 292

Abstract

Allergic diseases are caused by dysregulated Th2 immune responses involving multiple effector cells including basophils. Short chain fatty acids (SCFA......

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