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Mutations in Hnrnpa1 cause congenital heart defects

Yu, Z; Tang, PLF; Wang, J; Bao, SY; Shieh, JT; Leung, AWL; Zhang, Z; Gao, F; Wong, SYY; Hui, ALC; Gao, Y; Dung, N; Zhang, ZG; Fan, YH; Zhou, XY; Zhang, YL; Wong, DSM; Sham, PC; Azhar, A; Kwok, PY; Tam, PPL; Lian, QZ; Cheah, KSE; Wang, BB; Song, YQ

Song, YQ (reprint author), L3-63,Lab Block,21 Sassoon Rd, Hong Kong, Hong Kong, Peoples R China.; Cheah, KSE (reprint author), L3-73,Lab Block,21 Sassoon Rd, Hong Kong, Hong Kong, Peoples R China.; Wang, BB (reprint author), 12 Dahuisi Rd, Beijing 100081,

JCI INSIGHT, 2018; 3 (2):

Abstract

Incomplete penetrance of congenital heart defects (CHDs) was observed in a mouse model. We hypothesized that the contribution of a major genetic locus......

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