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Simultaneous Determination of 1-Methyltryptophan and Indoleamine 2,3-Dioxygenase Biomakers of Tryptophan and Kynurenine in Mice Tumors by HPLC-MS/MS

Zhou, LY; Zhu, RY; Lan, Y; Yang, JY; Sun, Y; Hou, YH; Ma, XQ; Liu, YH

Ma, XQ; Liu, YH (corresponding author), Ningxia Med Univ, Sch Pharm, Dept Pharmaceut, 1160 Shengli St, Yinchuan 750004, Ningxia, Peoples R China.; Ma, XQ; Liu, YH (corresponding author), Ningxia Med Univ, Minist Educ, Key Lab Hui Ethn Med Modernizat, Yinchuan 750004, Ningxia, Peoples R China.

CHROMATOGRAPHIA, 2021; 84 (7): 623

Abstract

Indoleamine 2,3-dioxygenase (IDO), an immune checkpoint protein, can cause the depletion of tryptophan (Trp) and accumulation of its metabolite of kyn......

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