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The Complex Effects of PKM2 and PKM2:IP3R Disruption on Intracellular Ca2+ Handling and Cellular Functions

Lemos, FO; de Ridder, I; Bootman, MD; Bultynck, G; Parys, JB

Lemos, FO; Parys, JB (通讯作者),Katholieke Univ Leuven, Dept Cellular & Mol Med, Lab Mol & Cellular Signaling, Herestr 49,Campus Gasthuisberg O&NI B802, B-3000 Leuven, Belgium.;Lemos, FO; Parys, JB (通讯作者),Katholieke Univ Leuven, Leuven Kanker Inst, Herestr 49,Campus Gasthuisberg O&NI B802, B-3000 Leuven, Belgium.

CELLS, 2023; 12 (21):

Abstract

Pyruvate kinase M (PKM) 2 was described to interact with the inositol 1,4,5-trisphosphate (IP3) receptor (IP3R) and suppress its activity. To further ......

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