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CHIP control degradation of mutant ETF:QO through ubiquitylation in late-onset multiple acyl-CoA dehydrogenase deficiency

Liu, XY; Chen, XJ; Zhao, M; Wang, ZQ; Chen, HZ; Li, HF; Wang, CJ; Wu, SF; Peng, C; Yin, Y; Fu, HX; Lin, MT; Yu, L; Xiong, ZQ; Wu, ZY; Wang, N

Wu, ZY (corresponding author), Zhejiang Univ, Sch Med, Dept Neurol, Hangzhou 310009, Zhejiang, Peoples R China.; Wu, ZY (corresponding author), Zhejiang Univ, Sch Med, Affiliated Hosp 2, Res Ctr Neurol, Hangzhou 310009, Zhejiang, Peoples R China.; Wu, ZY (corresponding author), Zhejiang Univ, Sch Med, Collaborat Innovat Ctr Brain Sci, Hangzhou 310009, Zhejiang, Peoples R China.; Wang, N (corresponding author), Fujian Med Univ, Affiliated Hosp 1, Dept Neurol, Fuzhou 350005, Fujian, Peoples R Chin

JOURNAL OF INHERITED METABOLIC DISEASE, ; ():

Abstract

Late-onset multiple acyl-CoA dehydrogenase deficiency (MADD) is the most common form of lipid storage myopathy. The disease is mainly caused by mutati......

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