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Defining the noninferiority margin and analysing noninferiority: An overview

Althunian, TA; de Boer, A; Groenwold, RHH; Klungel, OH

Klungel, OH (reprint author), Univ Utrecht, Div Pharmacoepidemiol & Clin Pharmacol, POB 80082, NL-3408 TB Utrecht, Netherlands.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2017; 83 (8): 1636

Abstract

Noninferiority trials are used to assess whether the effect of a new drug is not worse than an active comparator by more than a noninferiority margin.......

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