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Toxic Responses Induced at High Doses May Affect Benchmark Doses

Zarn, JA; Zurcher, UA; Geiser, HC

Zarn, JA (corresponding author), Fed Food Safety & Vet Off FSVO, Risk Assessment Div, Schwarzenburgstr 155, CH-3003 Bern, Switzerland.

DOSE-RESPONSE, 2020; 18 (2):

Abstract

To derive reference points (RPs) for health-based guidance values, the benchmark dose (BMD) approach increasingly replaces the no-observed-adverse-eff......

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