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The involvement of hepatic cytochrome P450s in the cytotoxicity of lapatinib

Chen, S; Li, XL; Li, YX; He, XB; Bryant, M; Qin, X; Li, F; Seo, JE; Guo, XQ; Mei, N; Guo, L

Chen, S; Guo, L (通讯作者),Natl Ctr Toxicol Res NCTR, Div Biochem Toxicol, 3900 NCTR Rd, Jefferson, AR 72079 USA.

TOXICOLOGICAL SCIENCES, 2023; 197 (1): 69

Abstract

Lapatinib, an oral tyrosine kinase inhibitor used as a first-line treatment for HER2-positive breast cancer, has been reported to be associated with h......

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