Multiple Sclerosis-Associated hnRNPA1 Mutations Alter hnRNPA1 Dynamics and Influence Stress Granule Formation-MedSci.cn

Multiple Sclerosis-Associated hnRNPA1 Mutations Alter hnRNPA1 Dynamics and Influence Stress Granule Formation

Clarke, JPWE; Thibault, PA; Salapa, HE; Kim, DE; Hutchinson, C; Levin, MC

Clarke, JPWE; Levin, MC (corresponding author), Univ Saskatchewan, Coll Med, Dept Hlth Sci, Saskatoon, SK S7N 5E5, Canada.; Clarke, JPWE; Levin, MC (corresponding author), Univ Saskatchewan, Off Saskatchewan Multiple Sclerosis Clin Res Chai, Saskatoon, SK S7K 0M7, Canada.; Levin, MC (corresponding author), Univ Saskatchewan, Dept Med, Neurol Div, Saskatoon, SK S7N 0X8, Canada.; Levin, MC (corresponding author), Univ Saskatchewan, Dept Anat Physiol & Pharmacol, Saskatoon, SK S7N 5E5, Canada.

Abstract

Evidence indicates that dysfunctional heterogeneous ribonucleoprotein A1 (hnRNPA1; A1) contributes to the pathogenesis of neurodegeneration in multipl......

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Multiple Sclerosis-Associated hnRNPA1 Mutations Alter hnRNPA1 Dynamics and Influence Stress Granule Formation

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