Angiotensin(1-7) activates MAS-1 and upregulates CFTR to promote insulin secretion in pancreatic beta-cells: the association with type 2 diabetes-MedSci.cn

Angiotensin(1-7) activates MAS-1 and upregulates CFTR to promote insulin secretion in pancreatic beta-cells: the association with type 2 diabetes

Zhang, XL; Zhao, XY; Wu, Y; Huang, WQ; Chen, JJ; Hu, PJ; Liu, W; Chen, YW; Hao, J; Xie, RR; Chan, HC; Ruan, YC; Chen, H; Guo, JH

Guo, JH (通讯作者)，Jinan Univ, Sch Med, Dept Physiol, Guangzhou, Peoples R China.;Chen, H (通讯作者)，Sun Yat Sen Univ, Cell Gene Therapy Translat Med Res Ctr, Affiliated Hosp 3, Guangzhou, Peoples R China.

Abstract

Objective: The beneficial effect of angiotensin(1-7) (Ang(1-7)), via the activation of its receptor, MAS-1, has been noted in diabetes treatment; howe......

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Angiotensin(1-7) activates MAS-1 and upregulates CFTR to promote insulin secretion in pancreatic beta-cells: the association with type 2 diabetes

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