Time-programmed activation of CD47 disruption and immunogenic cell death with Cas9 ribonucleoprotein nanocapsule for improved cancer immunotherapy-MedSci.cn

Time-programmed activation of CD47 disruption and immunogenic cell death with Cas9 ribonucleoprotein nanocapsule for improved cancer immunotherapy

Xing, YM; Yang, JH; Wang, C; Kang, ZY; Pan, Z; Tang, JH; Li, FH; Wang, X; Meng, XM; Cheng, ZF; Liu, Y; Liu, Q

Liu, Q (通讯作者)，Anhui Med Univ, Affiliated Hosp 2, Res Ctr Translat Med, Hefei 230032, Peoples R China.;Liu, Y (通讯作者)，Nankai Univ, Coll Chem, Minist Educ, State Key Lab Med Chem Biol,Key Lab Funct Polymer, Tianjin 300071, Peoples R China.;Cheng, ZF (通讯作者)，Anhui Univ Chinese Med, Sch Pharm, Anhui Prov Key Lab Pharmaceut Preparat Technol & A, Hefei 230012, Peoples R China.

Abstract

Cancer immunotherapy refers to activating the body's antitumor immunity to fight cancer cells, showing great potential in long-term inhibition of tumo......

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Time-programmed activation of CD47 disruption and immunogenic cell death with Cas9 ribonucleoprotein nanocapsule for improved cancer immunotherapy

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