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Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform

Visone, R; Lozano-Juan, F; Marzorati, S; Rivolta, MW; Pesenti, E; Redaelli, A; Sassi, R; Rasponi, M; Occhetta, P

Occhetta, P (通讯作者),Politecn Milan, Dept Elect Informat & Bioengn, I-20133 Milan, Italy.;Occhetta, P (通讯作者),BiomimX Srl, I-20158 Milan, Italy.

TOXICOLOGICAL SCIENCES, 2023; 191 (1): 47

Abstract

Determining the potential cardiotoxicity and pro-arrhythmic effects of drug candidates remains one of the most relevant issues in the drug development......

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