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Disruptin, a cell-penetrating peptide degrader of EGFR Cell-Penetrating Peptide in Cancer Therapy

Mehta, RK; Shukla, S; Ramanand, SG; Somnay, V; Bridges, AJ; Lawrence, TS; Nyati, MK

Nyati, MK (corresponding author), Univ Michigan, Dept Radiat Oncol, Ann Arbor, MI 48109 USA.

TRANSLATIONAL ONCOLOGY, 2021; 14 (8):

Abstract

Disruptin is a cell-permeable decoy peptide designed to destabilize activated EGFR, both by inhibiting Hsp90 chaperoning and dissociating the active a......

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