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Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements

Battaglia, S; Dong, K; Wu, JY; Chen, ZY; Najm, FJ; Zhang, YY; Moore, MM; Hecht, V; Shoresh, N; Bernstein, BE

Bernstein, BE (通讯作者),Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02115 USA.;Bernstein, BE (通讯作者),Broad Inst MIT & Harvard, Gene Regulat Observ, Cambridge, MA 02142 USA.;Bernstein, BE (通讯作者),Harvard Med Sch, Dept Cell Biol, Boston, MA 02115 USA.;Bernstein, BE (通讯作者),Harvard Med Sch, Dept Pathol, Boston, MA 02115 USA.

NATURE GENETICS, 2022; 54 (10): 1504

Abstract

Epigenomic maps identify gene regulatory elements by their chromatin state. However, prevailing short-read sequencing methods cannot effectively disti......

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