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Alirocumab efficacy in patients with double heterozygous, compound heterozygous, or homozygous familial hypercholesterolemia

Hartgers, ML; Defesche, JC; Langslet, G; Hopkins, PN; Kastelein, JJP; Baccara-Dinet, MT; Seiz, W; Hamon, S; Banerjee, P; Stefanutti, C

Stefanutti, C (reprint author), Sapienza Univ Rome, Umberto Hosp 1, Lipid Clin, Extracorporeal Therapeut Tech Unit, Rome, Italy.; Stefanutti, C (reprint author), Sapienza Univ Rome, Umberto Hosp 1, Atherosclerosis Prevent Ctr, Dept Mol Med,Immunohematol &

JOURNAL OF CLINICAL LIPIDOLOGY, 2018; 12 (2): 390

Abstract

BACKGROUND: Mutations in the genes for the low-density lipoprotein receptor (LDLR), apolipoprotein B, and proprotein convertase subtilisin/kexin type ......

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