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FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell

Relier, S; Ripoll, J; Guillorit, H; Amalric, A; Achour, C; Boissiere, F; Vialaret, J; Attina, A; Debart, F; Choquet, A; Macari, F; Marchand, V; Motorin, Y; Samalin, E; Vasseur, JJ; Pannequin, J; Aguilo, F; Lopez-Crapez, E; Hirtz, C; Rivals, E; Bastide, A; David, A

Bastide, A; David, A (corresponding author), Univ Montpellier, INSERM, CNRS, IGF, Montpellier, France.; Rivals, E (corresponding author), Univ Montpellier, CNRS, LIRMM, Montpellier, France.; David, A (corresponding author), Univ Montpellier, IRMB PPC, INSERM, CHU Montpellier,CNRS, Montpellier, France.

NATURE COMMUNICATIONS, 2021; 12 (1):

Abstract

Cancer stem cells (CSCs) are a small but critical cell population for cancer biology since they display inherent resistance to standard therapies and ......

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