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Protective Effects of Topiroxostat on an Ischemia-Reperfusion Model of Rat Hearts

Tanno, S; Yamamoto, K; Kurata, Y; Adachi, M; Inoue, Y; Otani, N; Mishima, M; Yamamoto, Y; Kuwabara, M; Ogino, K; Miake, J; Ninomiya, H; Shirayoshi, Y; Okada, F; Yamamoto, K; Hisatome, I

Kurata, Y (reprint author), Kanazawa Med Univ, Dept Physiol, 1-1 Daigaku, Uchinada, Ishikawa 9200293, Japan.

CIRCULATION JOURNAL, 2018; 82 (4): 1101

Abstract

Background: Ischemia/reperfusion (I/R) injury triggers cardiac dysfunctions via creating reactive oxygen species (ROS). Because xanthine oxidase (XO) ......

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