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Diversity-Oriented Peptide Stapling: A Third Generation Copper-Catalysed Azide-Alkyne Cycloaddition Stapling and Functionalisation Strategy

Tran, PT; Larsen, CO; Rondbjerg, T; De Foresta, M; Kunze, MBA; Marek, A; Loper, JH; Boyhus, LE; Knuhtsen, A; Lindorff-Larsen, K; Pedersen, DS

Pedersen, DS (reprint author), Univ Copenhagen, Dept Drug Design & Pharmacol, Univ Pk 2, DK-2100 Copenhagen, Denmark.

CHEMISTRY-A EUROPEAN JOURNAL, 2017; 23 (14): 3490

Abstract

The introduction of macrocyclic constraints in peptides (peptide stapling) is an important tool within peptide medicinal chemistry for stabilising and......

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