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Effects of splicing-regulatory polymorphisms in ABCC2, ABCG2, and ABCB1 on methotrexate exposure in Chinese children with acute lymphoblastic leukemia

Li, M; Kong, XY; Wang, SM

Wang, SM (通讯作者),Capital Med Univ, Beijing Shijitan Hosp, Dept Pharm, 10 Tieyi Rd, Beijing 100038, Peoples R China.;Wang, SM (通讯作者),Beijing Key Lab Biocharacterist Profiling Evaluat, Beijing 100038, Peoples R China.;Wang, SM (通讯作者),Int Cooperat & Joint Lab Biocharacterist Profiling, Beijing 100038, Peoples R China.

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2023; 91 (1): 77

Abstract

PurposeAdenosine triphosphate (ATP)-binding cassette (ABC) transporters play an important role in the response to methotrexate (MTX). In this study, w......

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