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Epigenetic Manipulation to Trigger Production of Guaiane-Type Sesquiterpenes from a Marine-Derived Spiromastix sp. Fungus with Antineuroinflammatory Effects

Guo, X; Meng, QY; Niu, SW; Liu, J; Guo, XC; Sun, ZL; Liu, D; Gu, YC; Huang, J; Fan, AL; Lin, WH

Fan, AL; Lin, WH (corresponding author), Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China.; Lin, WH (corresponding author), Peking Univ, Inst Ocean Res, Ningbo Inst Marine Med, Beijing 100191, Peoples R China.

JOURNAL OF NATURAL PRODUCTS, 2021; 84 (7): 1993

Abstract

Epigenetic manipulation of a deep-sea sediment-derived Spiromastix sp. fungus using suberoylanilide hydroxamic acid (SAHA) induction resulted in the a......

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