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GRB10 regulates beta-cell mass by inhibiting beta-cell proliferation and stimulating beta-cell dedifferentiation

Cai, ZX; Liu, F; Yang, Y; Li, DD; Hu, SB; Song, L; Yu, SJ; Li, T; Liu, BL; Luo, HR; Zhang, WP; Zhou, ZG; Zhang, JJ

Zhang, JJ (通讯作者),Cent South Univ, Natl Clin Res Ctr Metab Dis, Metab Syndrome Res Ctr, Key Lab Diabet Immunol,Minist Educ,Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.;Zhang, JJ (通讯作者),Cent South Univ, Dept Metab & Endocrinol, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.

JOURNAL OF GENETICS AND GENOMICS, 2022; 49 (3): 208

Abstract

Decreased functional beta-cell mass is the hallmark of diabetes, but the cause of this metabolic defect remains elusive. Here, we show that the levels......

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