Baidu
map

Functionally Null RAD51D Missense Mutation Associates Strongly with Ovarian Carcinoma

Rivera, B; Di Iorio, M; Frankum, J; Nadaf, J; Fahiminiya, S; Arcand, SL; Burk, DL; Grapton, D; Tomiak, E; Hastings, V; Hamel, N; Wagener, R; Aleynikova, O; Giroux, S; Hamdan, FF; Dionne-Laporte, A; Zogopoulos, G; Rousseau, F; Berghuis, AM; Provencher

Foulkes, WD (reprint author), McGill Univ, Hlth Ctr, Canc Res Program, 1001 Boul Decarie, Montreal, PQ H4A 3J1, Canada.

CANCER RESEARCH, 2017; 77 (16): 4517

Abstract

RAD51D is a key player in DNA repair by homologous recombination (HR), and RAD51D truncating variant carriers have an increased risk for ovarian cance......

Full Text Link


Baidu
map
Baidu
map
Baidu
map