Discovery and structural optimization of 3-O-beta-chacotriosyl oleanane-type triterpenoids as potent entry inhibitors of SARS-CoV-2 virus infections-MedSci.cn

Discovery and structural optimization of 3-O-beta-chacotriosyl oleanane-type triterpenoids as potent entry inhibitors of SARS-CoV-2 virus infections

Li, H; Cheng, C; Li, SM; Wu, Y; Liu, ZH; Liu, MJ; Chen, JX; Zhong, QY; Zhang, XS; Liu, SW; Song, GP

Song, GP (corresponding author), South China Agr Univ, Coll Mat & Energy, Minist Educ, Key Lab Biobased Mat & Energy, Guangzhou 510642, Peoples R China.; Liu, SW (corresponding author), Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R China.

Abstract

Currently, SARS-CoV-2 virus is an emerging pathogen that has posed a serious threat to public health worldwide. However, no agents have been approved ......

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Discovery and structural optimization of 3-O-beta-chacotriosyl oleanane-type triterpenoids as potent entry inhibitors of SARS-CoV-2 virus infections

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