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Novel bis-cyclic guanidines as potent membrane-active antibacterial agents with therapeutic potential

Teng, P; Nimmagadda, A; Su, M; Hong, YZ; Shen, N; Li, CP; Tsai, LY; Cao, J; Li, Q; Cai, JF

Cai, JF (reprint author), Univ S Florida, Dept Chem, Tampa, FL 33620 USA.; Li, Q (reprint author), Shanghai Univ Tradit Chinese Med, Shuguang Hosp, Dept Med Oncol, Shanghai 201203, Peoples R China.; Li, Q (reprint author), Shanghai Univ Tradit Chinese Med

CHEMICAL COMMUNICATIONS, 2017; 53 (87): 11948

Abstract

We designed a class of small dimeric cyclic guanidine derivatives which display potent antibacterial activity against both multidrug-resistant Gram-ne......

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