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MicroRNA-146a limits tumorigenic inflammation in colorectal cancer

Garo, LP; Ajay, AK; Fujiwara, M; Gabriely, G; Raheja, R; Kuhn, C; Kenyon, B; Skillin, N; Kadowaki-Saga, R; Saxena, S; Murugaiyan, G

Murugaiyan, G (corresponding author), Brigham & Womens Hosp, Dept Neurol, Ann Romney Ctr Neurol Dis, 75 Francis St, Boston, MA 02115 USA.; Murugaiyan, G (corresponding author), Harvard Med Sch, Boston, MA 02115 USA.

NATURE COMMUNICATIONS, 2021; 12 (1):

Abstract

Chronic inflammation can drive tumor development. Here, we have identified microRNA-146a (miR-146a) as a major negative regulator of colonic inflammat......

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