Inhibition of canine distemper virus replication by blocking pyrimidine nucleotide synthesis with A77 1726, the active metabolite of the anti-inflammatory drug leflunomide-MedSci.cn

Inhibition of canine distemper virus replication by blocking pyrimidine nucleotide synthesis with A77 1726, the active metabolite of the anti-inflammatory drug leflunomide

Li, Y; Yi, L; Cheng, SP; Wang, YS; Wang, JJ; Sun, J; Zhang, Q; Xu, XL

Xu, XL (corresponding author), Yangzhou Univ, Coll Vet Med, Inst Comparat Med, Yangzhou 225009, Jiangsu, Peoples R China.; Xu, XL (corresponding author), Yangzhou Univ, Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou 225009, Jiangsu, Peoples R China.; Xu, XL (corresponding author), Yangzhou Univ, Minist Educ China, Joint Int Res Lab Agr & Agriprod Safety, Inst Agr Sci, Yangzhou, Jiangsu, Peoples R China.; Xu, XL (corresponding author), Yangzhou Univ, Minist Educ China, Joint Int Res

Abstract

Canine distemper virus (CDV) is the aetiological agent that causes canine distemper (CD). Currently, no antiviral drugs have been approved for CD trea......

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Inhibition of canine distemper virus replication by blocking pyrimidine nucleotide synthesis with A77 1726, the active metabolite of the anti-inflammatory drug leflunomide

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