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ORCA/LRWD1 Regulates Homologous Recombination at ALT-Telomeres by Modulating Heterochromatin Organization

Hsu, RYC; Lin, YC; Redon, C; Sun, QY; Singh, DK; Wang, YT; Aggarwal, V; Mitra, J; Matur, A; Moriarity, B; Ha, T; Aladjem, MI; Prasanth, KV; Prasanth, SG

Prasanth, SG (corresponding author), Univ Illinois, Dept Cell & Dev Biol, 601S Goodwin Ave, Urbana, IL 61801 USA.; Prasanth, SG (corresponding author), UIUC, Canc Ctr Illinois, Urbana, IL 61801 USA.

ISCIENCE, 2020; 23 (5):

Abstract

Telomeres are maintained by telomerase or in a subset of cancer cells by a homologous recombination (HR)-based mechanism, Alternative Lengthening of T......

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