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An ELF4 hypomorphic variant results in NK cell deficiency

Salinas, SA; Mace, EM; Conte, MI; Park, CS; Li, Y; Rosario-Sepulveda, JI; Mahapatra, S; Moore, EK; Hernandez, ER; Chinn, IK; Reed, AE; Lee, BJ; Frumovitz, A; Gibbs, RA; Posey, JE; Satter, LRF; Thatayatikom, A; Allenspach, EJ; Wensel, TG; Lupski, JR; Lacorazza, HD; Orange, JS

Orange, JS (通讯作者),622 West 168th St,PH 17-201, New York, NY 10032 USA.

JCI INSIGHT, 2022; 7 (23):

Abstract

NK cell deficiencies (NKD) are a type of primary immune deficiency in which the major immunologic abnormality affects NK cell number, maturity, or fun......

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