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A BBE-like Oxidase, AsmF, Dictates the Formation of Naphthalenic Hydroxyl Groups in Ansaseomycin Biosynthesis

Liu, SH; Wei, YY; Xing, YN; Chen, Y; Wang, W; Wang, KB; Liang, Y; Jiao, RH; Zhang, B; Ge, HM

Jiao, RH; Zhang, B; Ge, HM (corresponding author), Nanjing Univ, Chem & Biomed Innovat Ctr, Sch Life Sci, Inst Funct Biomol,State Key Lab Pharmaceut Biotec, Nanjing 210023, Peoples R China.

ORGANIC LETTERS, 2021; 23 (9): 3724

Abstract

Ansaseomycins are ansamycin-type natural products produced through expression of the asm gene cluster in a heterologous host. A rare berberine bridge ......

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