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Enhancing anti-melanoma outcomes in mice using novel chitooligosaccharide nanoparticles loaded with therapeutic survivin-targeted siRNA

Liu, X; Chen, LQ; Zhang, YY; Xin, X; Qi, LL; Jin, MJ; Guan, YY; Gao, ZG; Huang, W

Gao, ZG; Huang, W (corresponding author), Chinese Acad Med Sci & Peking Union Med Coll, Inst Mat Med, Dept Pharmaceut, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China.; Guan, YY (corresponding author), Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr, Dept Urol, Natl Clin Res Ctr Canc,Canc Hosp, Beijing 100021, Peoples R China.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 158 ():

Abstract

Melanoma anti-tumor therapy remains a challenge. SiRNA-based therapies provide a powerful means, but limitations remain in its pharmaceutical applicat......

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