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DNA methylation of ITGB2 contributes to allopurinol hypersensitivity

Liu, Y; Wang, CW; Chen, CB; Yu, KH; Wu, YJ; Choon, SE; Chang, WC; Yang, FP; Luo, XQ; Chung, WH; Zhao, M; Lu, QJ

Zhao, M; Lu, QJ (通讯作者),Chinese Acad Med Sci & Peking Union Med Coll, Inst Dermatol, Nanjing, Peoples R China.;Chung, WH (通讯作者),Chang Gung Mem Hosp, Dept Dermatol, Linkou, Taiwan.;Zhao, M (通讯作者),Cent South Univ, Dept Dermatol, Hunan Key Lab Med Epigen, Xiangya Hosp 2, Changsha, Peoples R China.

CLINICAL IMMUNOLOGY, 2023; 248 ():

Abstract

Backgrounds: HLA-B*58:01 allele was strongly associated with allopurinol induced severe cutaneous adverse drug reaction (SCAR). However, HLA-B genotyp......

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