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研究表明:膝关节骨性关节炎注射类固醇激素无效!

2017-05-17 来宝网 来宝网

JAMA 发表的一项最新研究得出结论:有症状的膝关节骨性关节炎患者注射类固醇激素无效。 该研究的合着者,来自美国马萨诸塞州波士顿塔夫茨医学中心的 Timothy E. McAlindon 及其同事发现,对于膝关节骨性关节炎(OA)患者来说,每 3 个月注射一次类固醇激素的效果并不比一种缓解膝关节疼痛的安慰剂要好。 事实上,研究人员发现,实际上,注射类固醇激素超过 2 年以上



JAMA 发表的一项最新研究得出结论:有症状的膝关节骨性关节炎患者注射类固醇激素无效。

该研究的合着者,来自美国马萨诸塞州波士顿塔夫茨医学中心的 Timothy E. McAlindon 及其同事发现,对于膝关节骨性关节炎(OA)患者来说,每 3 个月注射一次类固醇激素的效果并不比一种缓解膝关节疼痛的安慰剂要好。

事实上,研究人员发现,实际上,注射类固醇激素超过 2 年以上会导致骨软骨量损失更多。

基于他们的发现,McAlindon 及其同事建议,停止使用类固醇激素注射进行膝关节骨性关节炎治疗。

骨性关节炎(OA),也称为退行性关节疾病,是最常见的一种关节炎,在美国大约有 3,000 多万名成年人患有此病。

目前还没有能够治愈骨性关节炎(OA)的方法,但可通过对症治疗控制症状的进展。

其中一种可能推荐的对症治疗方法就是注射皮质类固醇激素。已有一些研究表明,类固醇激素注射可缓解膝关节骨性关节炎(OA)患者的疼痛。

然而,这项最新研究表明,注射皮质类固醇激素对膝关节骨性关节炎患者是没有用的,甚至还会使病情恶化。

该研究小组在对 140 例有症状的膝关节骨性关节炎患者进行分析后得出以上结果。

McAlindon 及其同事认为,他们的研究结果表明,膝关节骨性关节炎患者不太可能从注射皮质类固醇激素中获益。研究人员总结道:

“我们的研究结果并不支持注射类固醇激素作为有症状的膝骨性关节炎患者的治疗方法。”(生物谷 Bioon.com)

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    2017-05-19 lmm397
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膝盖,是人体最大最复杂的关节。膝关节又是人体最大的承重关节,正常人的膝关节平均可承重35公斤。承受重量越多,关节软骨磨损的机率也越大,肌腱也容易受伤,膝关节退化较快。

Clin Nutr:地中海饮食还能降低骨关节炎风险!

本研究对北美洲的队列数据进行了分析,探究坚持地中海饮食能否降低膝关节骨关节炎发生率。 研究共纳入了4358名参与者(女性2527例;平均年龄:61.2岁),根据地中海饮食评分(aMED)对地中海饮食的坚持情况进行四分类。膝关节骨关节炎的诊断包括临床及放射学诊断。调整潜在的混杂因素后,通过Logistic回归分析,评估aMED(四分类)和膝关节骨关节炎之间的联系。 数据显示,对地中海饮食

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