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SABCS 2015:10年数据表明,早期乳癌选择保乳术+放疗优于乳房切除术

2015-12-11 MedSci MedSci原创

2015年圣安东尼奥乳癌研讨会上提供的数据表明,早期乳癌患者选择保乳术+放疗(BCT)与乳房切除术(不加放疗)相比,可显著改善10年后总生存。先前有观察性研究表明早期乳癌患者选择BCT比乳房切除术有更好的生存,但是这些观察性研究都有各自限制,绝大部分研究最多随访了5年时间而已。因此该结论是否具有广泛性还需要进一步大样本长期预后的随访。Siesling和同事根据荷兰癌症相关数据,纳入2000-200

2015年圣安东尼奥乳癌研讨会上提供的数据表明,早期乳癌患者选择保乳术+放疗(BCT)与乳房切除术(不加放疗)相比,可显著改善10年后总生存。先前有观察性研究表明早期乳癌患者选择BCT比乳房切除术有更好的生存,但是这些观察性研究都有各自限制,绝大部分研究最多随访了5年时间而已。因此该结论是否具有广泛性还需要进一步大样本长期预后的随访。Siesling和同事根据荷兰癌症相关数据,纳入2000-2004年间37,207名诊断为早期乳腺癌女性,探究不同治疗方式BCT和乳房切除术,其10年总生存(OS)是否存在差异;使用2003年诊断的7,552名患者组成的子队列数据探究两种治疗方式10年无病生存(DFS)的差异。总队列和子队列中接受BCT治疗的比例分别为58%和62%。研究数据显示,总队列中接受BCT治疗组10年OS为76.8%,而乳房切除术组该值为59.7%。子队列中BCT组10年DFS为83.6%,乳房切除组该值为81.5%。校正混杂因素后,BCT组比乳房切除组存活到10年以后的可能性大21%;但DFS在两组间差异不大。对子队列进行分析,结果相似。子队列的数据分析还显示,BCT组比乳房切

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    2016-08-03 1dd8c52fm63(暂无匿称)

    不错!

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=95616, encodeId=9d8f9561696, content=不错!, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Aug 03 05:50:00 CST 2016, time=2016-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1777043, encodeId=d7c51e7704315, content=<a href='/topic/show?id=45ae1e1830' target=_blank style='color:#2F92EE;'>#ABC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1718, encryptionId=45ae1e1830, topicName=ABC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a54039078223, createdName=cmj21wellington, createdTime=Fri Dec 18 06:36:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876747, encodeId=adf518e674788, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Mon Sep 12 23:36:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48506, encodeId=22ab4850622, content=好文章,值得看。, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sat Dec 26 17:22:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45790, encodeId=896a45e90f6, content=…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=176, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=554a1670659, createdName=yuwenpsy, createdTime=Sun Dec 13 22:29:00 CST 2015, time=2015-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587493, encodeId=bf94158e49374, content=<a href='/topic/show?id=e03515826f8' target=_blank style='color:#2F92EE;'>#SABCS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15826, encryptionId=e03515826f8, topicName=SABCS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=826117479684, createdName=guguangxiang, createdTime=Sun Dec 13 03:36:00 CST 2015, time=2015-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45674, encodeId=8911456e49c, content=还女性以尊严, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151119/IMG564D22F85A3BB6344.jpg, createdBy=750e1664472, createdName=De_dzw, createdTime=Sat Dec 12 10:58:00 CST 2015, time=2015-12-12, status=1, ipAttribution=)]
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    2015-12-26 hixiaoluo

    好文章,值得看。

    0

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    2015-12-13 yuwenpsy

    …………

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=95616, encodeId=9d8f9561696, content=不错!, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Aug 03 05:50:00 CST 2016, time=2016-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1777043, encodeId=d7c51e7704315, content=<a href='/topic/show?id=45ae1e1830' target=_blank style='color:#2F92EE;'>#ABC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1718, encryptionId=45ae1e1830, topicName=ABC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a54039078223, createdName=cmj21wellington, createdTime=Fri Dec 18 06:36:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876747, encodeId=adf518e674788, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Mon Sep 12 23:36:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48506, encodeId=22ab4850622, content=好文章,值得看。, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sat Dec 26 17:22:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45790, encodeId=896a45e90f6, content=…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=176, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=554a1670659, createdName=yuwenpsy, createdTime=Sun Dec 13 22:29:00 CST 2015, time=2015-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587493, encodeId=bf94158e49374, content=<a href='/topic/show?id=e03515826f8' target=_blank style='color:#2F92EE;'>#SABCS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15826, encryptionId=e03515826f8, topicName=SABCS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=826117479684, createdName=guguangxiang, createdTime=Sun Dec 13 03:36:00 CST 2015, time=2015-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45674, encodeId=8911456e49c, content=还女性以尊严, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151119/IMG564D22F85A3BB6344.jpg, createdBy=750e1664472, createdName=De_dzw, createdTime=Sat Dec 12 10:58:00 CST 2015, time=2015-12-12, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=95616, encodeId=9d8f9561696, content=不错!, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Aug 03 05:50:00 CST 2016, time=2016-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1777043, encodeId=d7c51e7704315, content=<a href='/topic/show?id=45ae1e1830' target=_blank style='color:#2F92EE;'>#ABC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1718, encryptionId=45ae1e1830, topicName=ABC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a54039078223, createdName=cmj21wellington, createdTime=Fri Dec 18 06:36:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876747, encodeId=adf518e674788, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Mon Sep 12 23:36:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48506, encodeId=22ab4850622, content=好文章,值得看。, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sat Dec 26 17:22:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45790, encodeId=896a45e90f6, content=…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=176, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=554a1670659, createdName=yuwenpsy, createdTime=Sun Dec 13 22:29:00 CST 2015, time=2015-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587493, encodeId=bf94158e49374, content=<a href='/topic/show?id=e03515826f8' target=_blank style='color:#2F92EE;'>#SABCS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15826, encryptionId=e03515826f8, topicName=SABCS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=826117479684, createdName=guguangxiang, createdTime=Sun Dec 13 03:36:00 CST 2015, time=2015-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45674, encodeId=8911456e49c, content=还女性以尊严, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151119/IMG564D22F85A3BB6344.jpg, createdBy=750e1664472, createdName=De_dzw, createdTime=Sat Dec 12 10:58:00 CST 2015, time=2015-12-12, status=1, ipAttribution=)]
    2015-12-12 De_dzw

    还女性以尊严

    0

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