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EClinical Med:武汉中南医院3674位职工新冠病毒无症状感染的发生率

2020-09-15 MedSci原创 MedSci原创

无症状携带者即新冠病毒(SARS-CoV-2)检测阳性,但没有相应的临床症状,这类人群可能是潜在的感染爆发源。本研究旨在明确普通人群中无症状携带者的流行病学和影响因素。

无症状携带者即新冠病毒(SARS-CoV-2)检测阳性,但没有相应的临床症状,这类人群可能是潜在的感染爆发源。本研究旨在明确普通人群中无症状携带者的流行病学和影响因素。

在武汉大学中南医院,所有医院员工都接受了咽拭子RT-PCR检测、血浆COVID-19 IgM/IgG抗体检测和胸部CT扫描。研究人员分析了感染率与员工性别、年龄、职务、工作地点和COVID-19知识培训之间的相关性。所有无症状感染者每周重测一次检测,连续3周。

(研究流程图)

总体上,共3764位医院员工被纳入本次单中心横断面研究。其中,126位医院职工有非正常结果,无症状感染率为0.76%(28/3674)。26位职工的IgM阳性(+),73位的IgG+,40位的胸部CT检查有磨玻璃影。

(三项检查的阳性情况)

所有发现异常的职工中,年龄越大,结果异常的可能性越大,且不受性别影响。在3674位职工中,一线工作人员的阳性率明显高于保健科员工(HCW)和行政人员。在COVID-19的治疗过程中,高风险科室和低风险科室之间的阳性率没有统计学上的显着差异。参加COVID-19知识培训的医护人员的阳性率低于未参加早期培训的医护人员。

(无感染、无症状感染者、确诊患者的IgM/IgG滴度)

要的是,无症状感染者的IgM抗体滴度与确诊的处于恢复期的COVID-19患者的没有统计学差异。在3周随访过程中,所有无症状感染者在隔离点积极干预的情况下均未出现临床症状或影像学异常。

(肺部磨玻璃影)

总结:为了确保复工的安全性,机构应为员工进行COVID-19预防培训并筛查无症状感染者,并在人口稠密的地区采取适当的隔离措施。


原始出处:


Fuling Zhou, et al. Tracing asymptomatic SARS-CoV-2 carriers among 3674 hospital staff:a cross-sectional survey. EClinical Medicine. September 14, 2020.

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    2020-09-26 122ba93am09(暂无昵称)

    不错

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1826637, encodeId=7e0e182663ee7, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sat Oct 03 12:38:20 CST 2020, time=2020-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1699510, encodeId=2ee7169951045, content=<a href='/topic/show?id=fe862163814' target=_blank style='color:#2F92EE;'>#中南医院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21638, encryptionId=fe862163814, topicName=中南医院)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=zhangpaul93, createdTime=Thu Nov 19 22:38:20 CST 2020, time=2020-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=888453, encodeId=a59f888453e1, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea162354528, createdName=122ba93am09(暂无昵称), createdTime=Sat Sep 26 06:46:40 CST 2020, time=2020-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485131, encodeId=9029148513189, content=<a href='/topic/show?id=4bbe5902ed2' target=_blank style='color:#2F92EE;'>#无症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Thu Sep 17 06:38:20 CST 2020, time=2020-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1507727, encodeId=7f27150e7278e, content=<a href='/topic/show?id=8764484014' target=_blank style='color:#2F92EE;'>#clinical#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4840, encryptionId=8764484014, topicName=clinical)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ee59933733, createdName=zll0628, createdTime=Thu Sep 17 06:38:20 CST 2020, time=2020-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610700, encodeId=232c1610e00ad, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Sep 17 06:38:20 CST 2020, time=2020-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=885799, encodeId=566b885e990a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Wed Sep 16 15:52:50 CST 2020, time=2020-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=885673, encodeId=f0318856e3df, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Wed Sep 16 08:21:27 CST 2020, time=2020-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028557, encodeId=310f102855e4d, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Tue Sep 15 18:38:20 CST 2020, time=2020-09-15, status=1, ipAttribution=)]
    2020-09-17 zll0628
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    2020-09-16 dhzzm

    学习了

    0

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    2020-09-16 14818eb4m67暂无昵称

    学习

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    2020-09-15 公卫新人

    新冠肺炎,疫情何时才能消失

    0

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