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Sci Rep:过敏性鼻炎是胃食管反流病的一种风险因素

2019-11-14 AlexYang MedSci原创

胃食管反流病(GERD)能够引起一些上呼吸道症状,并改变鼻咽粘膜的生理,而反过来上呼吸道疾病同样可能加剧GERD症状。长久以来,哮喘被认为是GERD的一种风险因素。根据相似的流行病学与病理生理学,哮喘和过敏性鼻炎(AR)通常被鉴定为联合气道疾病;然而,AR与GERD的相关性仍旧还没有阐明。最近,有研究人员评估了是否AR能够增加GERD的风险。研究人员从健康保险数据库中鉴定了诊断为AR的患者,时间为

食管反流病(GERD)能够引起一些上呼吸道症状,并改变鼻咽粘膜的生理,而反过来上呼吸道疾病同样可能加剧GERD症状。长久以来,哮喘被认为是GERD的一种风险因素。根据相似的流行病学与病理生理学,哮喘和过敏性鼻炎(AR)通常被鉴定为联合气道疾病;然而,AR与GERD的相关性仍旧还没有阐明。

最近,有研究人员评估了是否AR能够增加GERD的风险。研究人员从健康保险数据库中鉴定了诊断为AR的患者,时间为2000年1月1日和2005年12月31日,他们均没有食管反流病历史。研究人员关注的是新发的GERD。研究人员利用Cox回归模型计算了GERD的风险比(HR)。研究人员共分析了193810名年龄不小于18岁的AR患者数据,他们在基线时间点无AR。研究发现,AR群体(n=96905)比非AR群体(n=96905)具有显著更高的GERD风险(调整后HR (aHR) 1.94; 95% CI=1.88-1.99, p<0.001)。

最后,研究人员指出,AR可能比哮喘更强的与GERD的相关性,尽管哮喘与AR可能通过一些共有的途径来增加GERD的风险。

原始出处:


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    2019-11-16 zhouqu_8
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    2019-11-16 feifers
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    2019-11-15 14794e5bm67(暂无昵称)

    学习了,不错的话题,非常精彩,受益非浅

    0

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【1】Clin Otolaryngol:鼻用中药软膏Biyeom-go治疗鼻炎相关鼻症状的前瞻性观察研究 https://www.ncbi.nlm.nih.gov/pubmed/31468673最近,有研究人员调查了Biyeom-go在治疗鼻炎相关鼻症状中的效果和临床可行性情况。研究是一个前瞻性的观察性研究。研究包括了58名患有鼻炎的患者。所有的患者均接受每天大于3次的Biyeom-go治

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