Pain：确定儿童及青少年由急性MSK疼痛转为持续性痛的预测因子

2017-05-15 MedSci MedSci原创

预防伤残性疼痛的策略一直作为一项优先考虑的公共健康问题，早期识别处于预后结果较差的高风险年轻人至关重要。目前，关于预测处于由目前的急性疼痛转为持久性痛风险中的青少年的研究数据十分有限。该项前瞻性纵向研究旨在确定青少年在处于急性期的肌肉骨骼（MSK）痛转变持续性疼痛的生理、心理、社会预测因素。研究共纳入了88名因新发的（＜1个月）MSK疼痛而就诊于急救部门（n = 47）或整形外科诊所（N

预防伤残性疼痛的策略一直作为一项优先考虑的公共健康问题，早期识别处于预后结果较差的高风险年轻人至关重要。目前，关于预测处于由目前的急性疼痛转为持久性痛风险中的青少年的研究数据十分有限。该项前瞻性纵向研究旨在确定青少年在处于急性期的肌肉骨骼（MSK）痛转变持续性疼痛的生理、心理、社会预测因素。

研究共纳入了88名因新发的（＜1个月）MSK疼痛而就诊于急救部门（n = 47）或整形外科诊所（N = 41）的儿童和青少年（年龄为10-17岁）。两次随访（T1在疼痛发作后≤1个月；T2 = 4个月的随访），这期间完成问卷调查（评估其疼痛特点、心理因素、睡眠质量），此外，研究对象还参加实验室研究，评估其条件疼痛调制。回归分析评估纵向疼痛的结果T1预测因子（疼痛持续性，疼痛相关的残疾，生活质量[QOL]）。

结果显示，约35%的青少年在4个月的随访时有持续性疼痛，较差的条件疼痛调制和女性性别可预测持续性疼痛。T1时较高的抑郁症状与T2时较高的疼痛相关的残疾和较差的QOL相关。结果强调了在因MSK疼痛寻求治疗的青少年中，抑郁的症状和条件疼痛调制作用在纵向预测疼痛持续性中的作用，并提示了儿童和青少年从急性到慢性MSK疼痛的转变机制。

原始出处：

Holley AL, Wilson AC, Palermo TM. Predictors of the transition from acute to persistent musculoskeletal pain in children andadolescents: a prospective study. Pain. 2017 May;158(5):794-801. doi: 10.1097/j.pain.0000000000000817.

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2017-06-13 liuyg0228

#持续性#

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2017-05-21 1e145228m78(暂无匿称)

学习了，谢谢作者分享!

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2017-05-17 宋威

#预测因子#

86 0
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2017-05-16 天涯183

非常好的文章，学习了，很受益

76 0
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2017-05-16 明月清辉

谢谢分享，学习

106 0
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2017-05-16 Y—xianghai

看了，有些地方看不懂。

66 0
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2017-05-16 半夏微凉

学习了谢谢分享

73 0
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encodeId=d9ac1985e7ed, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue May 16 02:22:59 CST 2017, time=2017-05-16, status=1, ipAttribution=)]
2017-05-16 1e10c84am36(暂无匿称)

文章很好，值得拜读

48 0
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2017-05-16 刘煜

学习了谢谢分享

41 0
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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Tue May 16 12:46:34 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198705, encodeId=eb1f198e0505, content=谢谢分享，学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Tue May 16 08:17:30 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198670, encodeId=3b4b1986e08b, content=看了，有些地方看不懂。, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue May 16 07:04:19 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198635, encodeId=db37198635dc, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Tue May 16 06:17:21 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198631, encodeId=ec12198631f4, content=文章很好，值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue May 16 06:15:55 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198613, encodeId=574a1986139e, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue May 16 06:02:16 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198577, encodeId=d9ac1985e7ed, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue May 16 02:22:59 CST 2017, time=2017-05-16, status=1, ipAttribution=)]
2017-05-16 飛歌

学习了很有用

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