Baidu
map

Ann Surg:新辅助放疗VS.单纯手术治疗有或无高危因素的II/III期直肠癌的疗效

2021-05-09 MedSci原创 MedSci原创

新辅助放疗(NRT)通常用于II/III期直肠癌,以改善局部控制,同时不影响总体生存。然而,在某些患者中,仅靠高水平手术也可以达到良好的局部控制。近日,研究人员探究了有或没有高危因素的II/III期直

新辅助放疗(NRT)通常用于II/III期直肠癌,以改善局部控制,同时不影响总体生存。然而,在某些患者中,仅靠高水平手术也可以达到良好的局部控制。近日,研究人员探究了有或没有高危因素的II/III期直肠癌中新辅助放疗(NRT)的治疗效果,研究结果已发表于 Ann Surg。

根据风险分层标准和临床分期,纳入符合条件的II/III期直肠癌参与者,术前分为有(高风险)或无(低风险)高风险因素的患者,分别随机接受短程放疗(SCRT)+全直肠系膜切除术(TME)或单纯TME,分为以下4组:高危患者接受(HiR)或不接受(HiS)放射治疗,低危患者接受(LoR)或不接受(LoS)放射治疗。主要终点是局部复发。次要终点包括总生存期、无病生存期、远处复发、手术质量和安全性。

 

共有401名患者纳入最终分析。中位随访54个月,低风险患者获得了比高风险患者更低的3年累计局部复发率(2.2% vs 11.0%,P = 0.006)和累计远处复发率(12.5% vs 29.4%,P < 0.001),更高的总生存率(86.9% vs 76.5%,P = 0.002)和无病生存率(87.0% vs 67.9%,P < 0.001)。关于局部复发的3年累积发生率,LoR组和LoS组(1.2% vs 3.0%,P = 0.983)或HiR组和HiS组(12.9% vs 8.9%,P = 0.483)之间没有差异。

总之,该研究结果表明,根据风险因素对II/III期直肠癌进行分层,使之成为更精确的亚分类,可能会在存活率和局部复发控制方面产生差异。仅仅通过前期良好的手术质量,就可以在低风险患者中实现极低的局部复发累积发生率和生存率。研究的局限性在于不能证明单纯手术的非劣效性,建议根据II/III期直肠癌的临床风险分层,有针对性地使用NRT。

 

原始出处:

 

Xiangbing Deng, et al., Neoadjuvant Radiotherapy Versus Surgery Alone for Stage II/III Mid-low Rectal Cancer With or Without High-risk Factors: A Prospective Multicenter Stratified Randomized Trial. Ann Surg. 2020 Dec;272(6):1060-1069. doi: 10.1097/SLA.0000000000003649.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1678672, encodeId=6e7016e867256, content=<a href='/topic/show?id=110c5869153' target=_blank style='color:#2F92EE;'>#新辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58691, encryptionId=110c5869153, topicName=新辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=941f27706894, createdName=charl1234576, createdTime=Mon Jan 03 08:11:34 CST 2022, time=2022-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1689916, encodeId=292b16899167a, content=<a href='/topic/show?id=8d7e58699ab' target=_blank style='color:#2F92EE;'>#新辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58699, encryptionId=8d7e58699ab, topicName=新辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=557928916517, createdName=12498e5fm21(暂无昵称), createdTime=Mon Aug 16 02:11:34 CST 2021, time=2021-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1916426, encodeId=93cc1916426fd, content=<a href='/topic/show?id=c5a89550ff' target=_blank style='color:#2F92EE;'>#III#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9550, encryptionId=c5a89550ff, topicName=III)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Sun Dec 19 03:11:34 CST 2021, time=2021-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290769, encodeId=b77c1290e69f5, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568311, encodeId=6f5615683116a, content=<a href='/topic/show?id=f5d69368591' target=_blank style='color:#2F92EE;'>#辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93685, encryptionId=f5d69368591, topicName=辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=135c15357385, createdName=xuyu, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594883, encodeId=d6db1594883f9, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032904, encodeId=02221032904e8, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Mon May 10 01:11:34 CST 2021, time=2021-05-10, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1678672, encodeId=6e7016e867256, content=<a href='/topic/show?id=110c5869153' target=_blank style='color:#2F92EE;'>#新辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58691, encryptionId=110c5869153, topicName=新辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=941f27706894, createdName=charl1234576, createdTime=Mon Jan 03 08:11:34 CST 2022, time=2022-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1689916, encodeId=292b16899167a, content=<a href='/topic/show?id=8d7e58699ab' target=_blank style='color:#2F92EE;'>#新辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58699, encryptionId=8d7e58699ab, topicName=新辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=557928916517, createdName=12498e5fm21(暂无昵称), createdTime=Mon Aug 16 02:11:34 CST 2021, time=2021-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1916426, encodeId=93cc1916426fd, content=<a href='/topic/show?id=c5a89550ff' target=_blank style='color:#2F92EE;'>#III#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9550, encryptionId=c5a89550ff, topicName=III)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Sun Dec 19 03:11:34 CST 2021, time=2021-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290769, encodeId=b77c1290e69f5, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568311, encodeId=6f5615683116a, content=<a href='/topic/show?id=f5d69368591' target=_blank style='color:#2F92EE;'>#辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93685, encryptionId=f5d69368591, topicName=辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=135c15357385, createdName=xuyu, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594883, encodeId=d6db1594883f9, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032904, encodeId=02221032904e8, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Mon May 10 01:11:34 CST 2021, time=2021-05-10, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1678672, encodeId=6e7016e867256, content=<a href='/topic/show?id=110c5869153' target=_blank style='color:#2F92EE;'>#新辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58691, encryptionId=110c5869153, topicName=新辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=941f27706894, createdName=charl1234576, createdTime=Mon Jan 03 08:11:34 CST 2022, time=2022-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1689916, encodeId=292b16899167a, content=<a href='/topic/show?id=8d7e58699ab' target=_blank style='color:#2F92EE;'>#新辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58699, encryptionId=8d7e58699ab, topicName=新辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=557928916517, createdName=12498e5fm21(暂无昵称), createdTime=Mon Aug 16 02:11:34 CST 2021, time=2021-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1916426, encodeId=93cc1916426fd, content=<a href='/topic/show?id=c5a89550ff' target=_blank style='color:#2F92EE;'>#III#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9550, encryptionId=c5a89550ff, topicName=III)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Sun Dec 19 03:11:34 CST 2021, time=2021-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290769, encodeId=b77c1290e69f5, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568311, encodeId=6f5615683116a, content=<a href='/topic/show?id=f5d69368591' target=_blank style='color:#2F92EE;'>#辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93685, encryptionId=f5d69368591, topicName=辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=135c15357385, createdName=xuyu, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594883, encodeId=d6db1594883f9, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032904, encodeId=02221032904e8, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Mon May 10 01:11:34 CST 2021, time=2021-05-10, status=1, ipAttribution=)]
    2021-12-19 juliusluan78
  4. [GetPortalCommentsPageByObjectIdResponse(id=1678672, encodeId=6e7016e867256, content=<a href='/topic/show?id=110c5869153' target=_blank style='color:#2F92EE;'>#新辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58691, encryptionId=110c5869153, topicName=新辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=941f27706894, createdName=charl1234576, createdTime=Mon Jan 03 08:11:34 CST 2022, time=2022-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1689916, encodeId=292b16899167a, content=<a href='/topic/show?id=8d7e58699ab' target=_blank style='color:#2F92EE;'>#新辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58699, encryptionId=8d7e58699ab, topicName=新辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=557928916517, createdName=12498e5fm21(暂无昵称), createdTime=Mon Aug 16 02:11:34 CST 2021, time=2021-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1916426, encodeId=93cc1916426fd, content=<a href='/topic/show?id=c5a89550ff' target=_blank style='color:#2F92EE;'>#III#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9550, encryptionId=c5a89550ff, topicName=III)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Sun Dec 19 03:11:34 CST 2021, time=2021-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290769, encodeId=b77c1290e69f5, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568311, encodeId=6f5615683116a, content=<a href='/topic/show?id=f5d69368591' target=_blank style='color:#2F92EE;'>#辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93685, encryptionId=f5d69368591, topicName=辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=135c15357385, createdName=xuyu, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594883, encodeId=d6db1594883f9, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032904, encodeId=02221032904e8, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Mon May 10 01:11:34 CST 2021, time=2021-05-10, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1678672, encodeId=6e7016e867256, content=<a href='/topic/show?id=110c5869153' target=_blank style='color:#2F92EE;'>#新辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58691, encryptionId=110c5869153, topicName=新辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=941f27706894, createdName=charl1234576, createdTime=Mon Jan 03 08:11:34 CST 2022, time=2022-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1689916, encodeId=292b16899167a, content=<a href='/topic/show?id=8d7e58699ab' target=_blank style='color:#2F92EE;'>#新辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58699, encryptionId=8d7e58699ab, topicName=新辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=557928916517, createdName=12498e5fm21(暂无昵称), createdTime=Mon Aug 16 02:11:34 CST 2021, time=2021-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1916426, encodeId=93cc1916426fd, content=<a href='/topic/show?id=c5a89550ff' target=_blank style='color:#2F92EE;'>#III#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9550, encryptionId=c5a89550ff, topicName=III)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Sun Dec 19 03:11:34 CST 2021, time=2021-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290769, encodeId=b77c1290e69f5, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568311, encodeId=6f5615683116a, content=<a href='/topic/show?id=f5d69368591' target=_blank style='color:#2F92EE;'>#辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93685, encryptionId=f5d69368591, topicName=辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=135c15357385, createdName=xuyu, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594883, encodeId=d6db1594883f9, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032904, encodeId=02221032904e8, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Mon May 10 01:11:34 CST 2021, time=2021-05-10, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1678672, encodeId=6e7016e867256, content=<a href='/topic/show?id=110c5869153' target=_blank style='color:#2F92EE;'>#新辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58691, encryptionId=110c5869153, topicName=新辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=941f27706894, createdName=charl1234576, createdTime=Mon Jan 03 08:11:34 CST 2022, time=2022-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1689916, encodeId=292b16899167a, content=<a href='/topic/show?id=8d7e58699ab' target=_blank style='color:#2F92EE;'>#新辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58699, encryptionId=8d7e58699ab, topicName=新辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=557928916517, createdName=12498e5fm21(暂无昵称), createdTime=Mon Aug 16 02:11:34 CST 2021, time=2021-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1916426, encodeId=93cc1916426fd, content=<a href='/topic/show?id=c5a89550ff' target=_blank style='color:#2F92EE;'>#III#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9550, encryptionId=c5a89550ff, topicName=III)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Sun Dec 19 03:11:34 CST 2021, time=2021-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290769, encodeId=b77c1290e69f5, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568311, encodeId=6f5615683116a, content=<a href='/topic/show?id=f5d69368591' target=_blank style='color:#2F92EE;'>#辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93685, encryptionId=f5d69368591, topicName=辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=135c15357385, createdName=xuyu, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594883, encodeId=d6db1594883f9, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032904, encodeId=02221032904e8, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Mon May 10 01:11:34 CST 2021, time=2021-05-10, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1678672, encodeId=6e7016e867256, content=<a href='/topic/show?id=110c5869153' target=_blank style='color:#2F92EE;'>#新辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58691, encryptionId=110c5869153, topicName=新辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=941f27706894, createdName=charl1234576, createdTime=Mon Jan 03 08:11:34 CST 2022, time=2022-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1689916, encodeId=292b16899167a, content=<a href='/topic/show?id=8d7e58699ab' target=_blank style='color:#2F92EE;'>#新辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58699, encryptionId=8d7e58699ab, topicName=新辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=557928916517, createdName=12498e5fm21(暂无昵称), createdTime=Mon Aug 16 02:11:34 CST 2021, time=2021-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1916426, encodeId=93cc1916426fd, content=<a href='/topic/show?id=c5a89550ff' target=_blank style='color:#2F92EE;'>#III#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9550, encryptionId=c5a89550ff, topicName=III)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Sun Dec 19 03:11:34 CST 2021, time=2021-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290769, encodeId=b77c1290e69f5, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568311, encodeId=6f5615683116a, content=<a href='/topic/show?id=f5d69368591' target=_blank style='color:#2F92EE;'>#辅助放疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93685, encryptionId=f5d69368591, topicName=辅助放疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=135c15357385, createdName=xuyu, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1594883, encodeId=d6db1594883f9, content=<a href='/topic/show?id=b317956200' target=_blank style='color:#2F92EE;'>#III期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9562, encryptionId=b317956200, topicName=III期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Tue May 11 13:11:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032904, encodeId=02221032904e8, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Mon May 10 01:11:34 CST 2021, time=2021-05-10, status=1, ipAttribution=)]
    2021-05-10 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

相关资讯

Gastroenterology:青春期时高糖食物和含糖饮料要少吃喝,或显著增加成年后结直肠癌患病风险!

高脂高糖的饮食习惯被认为可能是CRC发病率上升的原因之一。

Cancer Discovery:邹伟平团队揭示视神经蛋白缺失介导结直肠癌免疫逃逸的机制

尽管免疫治疗在黑色素瘤和肺癌中取得重要进展,但在结直肠癌中却收益甚微。目前免疫治疗仅对部分微卫星高度不稳定或错配修复缺陷的结直肠癌患者有效,然而这类病人仅占结直肠癌患者总数的15%,绝大多数结直肠癌患

日本音乐家坂本龙一确诊直肠癌!八成患者确诊直肠癌已是中晚期

核心提示:研究显示,七分之一的结直肠癌患者年龄小于50岁,这一比例已经不算小,再加上年轻患者占比有上升趋势、确诊时多为晚期病变、比老年人更容易发生区域淋巴结转移等特点,提示我们:即使是正值青壮年,也该

Radiology:直肠癌术前分期使人愁,MRI新征象来解忧

近年来,由于结直肠癌常规筛查的增加和居民查体意识的增强,早期直肠癌的发现越来越普遍。全肠系膜切除术已被临床广泛应用于直肠癌患者的根治性治疗,术后患者的预后得到显著改善。

Lancet Gastroen Hepatol:短期放疗联合经肛门内镜显微手术治疗早期直肠癌

对于早期直肠癌患者,短期放疗后进行经肛门内镜显微手术在疾病控制方面的效果与全直肠系膜切除相当,但在患者生活质量改善方面优于全直肠系膜切除

Baidu
map
Baidu
map
Baidu
map