Heart：这类先心病手术不应在婴儿期进行！

2018-06-03 MedSci MedSci原创

部分性房室间隔缺损（pAVSD）修复术的时机一般是2-4岁，预后很好，但婴儿期的修复术预后会较差。本研究的目的旨在评估婴儿期的pAVSD手术对患者预后的影响。本研究纳入了1975-2015年接受pAVSD修复术治疗的患儿，并将婴儿（＜1岁）与年龄较大儿童进行了倾向性评分匹配分析。最终共纳入了430名患儿，其中17.4%为婴儿，与年龄较大儿童相比，婴儿发生左房室瓣反流（LAVV）、心衰和其他心脏疾病

部分性房室间隔缺损（pAVSD）修复术的时机一般是2-4岁，预后很好，但婴儿期的修复术预后会较差。本研究的目的旨在评估婴儿期的pAVSD手术对患者预后的影响。

本研究纳入了1975-2015年接受pAVSD修复术治疗的患儿，并将婴儿（＜1岁）与年龄较大儿童进行了倾向性评分匹配分析。最终共纳入了430名患儿，其中17.4%为婴儿，与年龄较大儿童相比，婴儿发生左房室瓣反流（LAVV）、心衰和其他心脏疾病的风险更高，且婴儿的30年生存率明显更低（82.1% ； 95% CI 70.1%- 89.6% vs 95.7% ； 95% CI 91.3% -97.9%； P<0.001），倾向性评分匹配分析后发现婴儿的30年生存率依旧更低（p=0.04），但在二次手术率方面无明显差异。

研究结果显示，婴儿期接受部分性房室间隔缺损修复术的患儿生存率更低，这类患儿应推迟至1岁以后治疗。

原始出处：

Edward B et al.Propensity score matched analysis of partial atrioventricular septal defect repair in infancy.Heart.2018 May.

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2018-06-05 ssnine

#先心病#

66 0
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2018-06-05 zhaojie88

#ART#

56 0
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2018-06-05 slcumt

#HEART#

0 0
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2018-06-05 108807375_62823133

#婴儿期#

67 0
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2018-06-05 三生有幸9135

学习一下谢谢分享

109 0
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2018-06-04 smartxiuxiu

好

101 0
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2018-06-04 1209e435m98(暂无昵称)

学习了.谢谢分享

122 0
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2018-06-03 1e145228m78(暂无匿称)

学习了.谢谢作者分享!

97 0

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