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Semin Arthritis Rheu:巨细胞动脉炎和风湿性多肌痛的发病率和患病率

2020-07-25 xiangting MedSci原创

该SLR提供了全世界不同人群GCA和PMR发生率的最新估算值。北欧血统人群中GCA的发病率较高。

巨细胞动脉炎(GCA;有时也称为颞动脉炎)和风湿性多肌痛(PMR)是常见且相互关联的炎症性疾病,几乎专门影响50岁以上的成年人。需要关于这些疾病的最新流行病学信息。

这项系统性文献综述(SLR)旨在总结关于GCA和PMR发病率和患病率的最新证据。

检索PubMed和Google学术数据库2019年7月30日以前发表的相关文章。确定了报道GCA和/或PMR发病率和/或患病率的研究。如果是对同一人群进行了多项研究,则使用最新的。系统回顾了有关来源人群和病例验证的详细信息。结果按世界上的地区列出。

经过2位作者的筛选,得到了2643篇摘要,其中77篇文章符合纳入标准。与PMR相比,GCA的研究更多,发病率研究多于患病率研究。在研究设计和研究人群上存在很大差异。包括详尽病例验证的研究倾向于给出较低的估算值,尤其是对于PMR。来自斯堪的纳维亚和英国(14.6-43.6)以及美国明尼苏达州的研究(每10万人口19.8)中,≥50岁每10万人口的GCA发病率最高。南欧的相应估算值较低(1.1-11.1)。有限的证据表明,GCA和PMR在非高加索人群中较少见。白人PMR的患病率估算值比GCA高3倍以上。

该SLR提供了全世界不同人群GCA和PMR发生率的最新估算值。北欧血统人群中GCA的发病率较高。关于PMR流行病学的数据更为有限,发病率和患病率的估算值也存在较大差异。

原始出处:

Ankita Sharma. Incidence and Prevalence of Giant Cell Arteritis and Polymyalgia Rheumatica: A Systematic Literature Review. Semin Arthritis Rheu. 14 July 2020.

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    2021-04-26 xsm927
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    2020-07-27 zhaojie88
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    2020-07-27 wwzzly

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