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FASEB J:孕妇多吃富含胆碱的食物 将来宝宝会更加聪明

2018-01-10 佚名 “细胞”微信号

近日,一篇发表在国际杂志The FASEB Journal上的研究报告中,来自康奈尔大学的研究人员通过研究发现,当女性在孕期摄入足够水平的营养胆碱时,其后代将会获得更为持久的认知优势/益处,胆碱有多种功能,其在多种食物中都存在,比如蛋黄、瘦肉(红肉)、鱼肉、禽肉、豆类、坚果和十字花科蔬菜等,本文重点研究了胆碱在婴儿出生前大脑发育上所扮演的关键角色。

近日,一篇发表在国际杂志The FASEB Journal上的研究报告中,来自康奈尔大学的研究人员通过研究发现,当女性在孕期摄入足够水平的营养胆碱时,其后代将会获得更为持久的认知优势/益处,胆碱有多种功能,其在多种食物中都存在,比如蛋黄、瘦肉(红肉)、鱼肉、禽肉、豆类、坚果和十字花科蔬菜等,本文重点研究了胆碱在婴儿出生前大脑发育上所扮演的关键角色。

研究人员表示,在怀孕最后三个月里摄入胆碱水平相当于推荐水平两倍的孕妇,其后代将会获得较大的认知益处;研究者Marie Caudill教授说道,在动物模型中我们得到了一致性的结论,即在母源性饮食中补充单一营养素(胆碱)会给后代的认知功能带来终生的益处,而相应的结果似乎在人类机体中也同样适用。这项研究非常重要,因为在女性孕期其对胆碱的需求量较高,然而大部分女性每日摄入的胆碱水平还不到450毫克的推荐量。

研究者Richard Canfield指出,这或许部分是由于目前的饮食趋势和做法导致的,很多富含胆碱的食物目前或许“名声”并不太好,比如鸡蛋,其富含胆固醇,而且包括在政府工作的健康专家都对孕妇摄入未煮熟的鸡蛋提出了警示,这或许会阻止女性摄入鸡蛋,尽管相应的健康风险在巴士杀菌和煮熟的鸡蛋中是很小的,而且在摄入红肉时通常要避免摄入过多脂肪。

在此前的两项研究中,研究人员想通过研究阐明母源性胆碱补充对婴儿认知功能的效应,但这两项研究得出了并不一致的结论,这或许是由于研究设计并未受到严格控制所导致的。这项研究中,研究人员将26名女性随机分为两组,所有女性都摄入相同的饮食,此外研究人员对参与者的胆碱和其它营养物质的摄入进行严格控制,通过确保所有的营养成分都是等量的,研究人员发现了胆碱摄入对婴儿认知功能的差异,文章中,其中一半女性胆碱的摄入量为480mg/天,略高于适当的摄入量,而另外一组女性的胆碱摄入量则为930 mg/天。

随后研究人员在4个月、7个月、10个月及13个月时检测了婴儿的信息处理速度和视觉空间记忆,他们计算了每个婴儿观察电脑屏幕边缘图像的时间,这个测定参数是婴儿产生运动反应的线索,这项测试与婴儿在儿童期的IQ直接相关,此外,研究人员还发现,信息处理速度较快的婴儿,当其年龄增长时其处理信息的速度依然很快。

结果表明,在同一时期,相比胆碱摄入水平为480mg/天的孕妇而言,胆碱摄入水平为930mg/天的孕妇所生的婴儿在认知功能、信息处理速度上会明显加快;尽管这项研究中样本量较少,但相关研究结果表明,每日摄入推荐剂量的胆碱似乎并不足以对后代的大脑认知发育产生最佳的影响,最后研究者Canfield说道,当前的胆碱摄入推荐量是基于需要预测肝功能障碍的水平来设定的,而且这是从男性的研究中推断出来的,这或许部分是因为目前并没有研究人员对孕期女性进项相关研究所致,当然后期研究人员还需要对更多的孕妇进行相关研究来证实胆碱对后代大脑认知功能的有益影响。

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    2018-04-02 gracezdd
  2. 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    2018-01-19 飞鸟与鱼

    谢谢分享!

    0

  3. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/31/a88428e95e462b5a95499ced50b4325e.jpg, createdBy=60182225250, createdName=15121100f4m, createdTime=Thu Jan 11 06:03:32 CST 2018, time=2018-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277258, encodeId=05872e7258a2, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Jan 10 17:49:30 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1249819, encodeId=767f1249819dc, content=<a href='/topic/show?id=95264599452' target=_blank style='color:#2F92EE;'>#宝宝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45994, encryptionId=95264599452, topicName=宝宝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=杏林小小, createdTime=Wed Jan 10 17:22:00 CST 2018, time=2018-01-10, status=1, ipAttribution=)]
    2018-01-12 Jackie Li

    学习

    0

  4. 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target=_blank style='color:#2F92EE;'>#宝宝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45994, encryptionId=95264599452, topicName=宝宝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=杏林小小, createdTime=Wed Jan 10 17:22:00 CST 2018, time=2018-01-10, status=1, ipAttribution=)]
    2018-01-12 yhy100201
  5. 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    2018-01-12 grace5704
  6. 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target=_blank style='color:#2F92EE;'>#宝宝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45994, encryptionId=95264599452, topicName=宝宝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=杏林小小, createdTime=Wed Jan 10 17:22:00 CST 2018, time=2018-01-10, status=1, ipAttribution=)]
    2018-01-12 Boyinsh
  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/31/a88428e95e462b5a95499ced50b4325e.jpg, createdBy=60182225250, createdName=15121100f4m, createdTime=Thu Jan 11 06:03:32 CST 2018, time=2018-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277258, encodeId=05872e7258a2, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Jan 10 17:49:30 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1249819, encodeId=767f1249819dc, content=<a href='/topic/show?id=95264599452' target=_blank style='color:#2F92EE;'>#宝宝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45994, encryptionId=95264599452, topicName=宝宝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=杏林小小, createdTime=Wed Jan 10 17:22:00 CST 2018, time=2018-01-10, status=1, ipAttribution=)]
    2018-01-11 董海鹏

    实践是检验真理的

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/31/a88428e95e462b5a95499ced50b4325e.jpg, createdBy=60182225250, createdName=15121100f4m, createdTime=Thu Jan 11 06:03:32 CST 2018, time=2018-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277258, encodeId=05872e7258a2, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Jan 10 17:49:30 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1249819, encodeId=767f1249819dc, content=<a href='/topic/show?id=95264599452' target=_blank style='color:#2F92EE;'>#宝宝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45994, encryptionId=95264599452, topicName=宝宝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=杏林小小, createdTime=Wed Jan 10 17:22:00 CST 2018, time=2018-01-10, status=1, ipAttribution=)]
    2018-01-11 15121100f4m

    看来老祖宗说的是有道理的.

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/31/a88428e95e462b5a95499ced50b4325e.jpg, createdBy=60182225250, createdName=15121100f4m, createdTime=Thu Jan 11 06:03:32 CST 2018, time=2018-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277258, encodeId=05872e7258a2, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Jan 10 17:49:30 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1249819, encodeId=767f1249819dc, content=<a href='/topic/show?id=95264599452' target=_blank style='color:#2F92EE;'>#宝宝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45994, encryptionId=95264599452, topicName=宝宝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=杏林小小, createdTime=Wed Jan 10 17:22:00 CST 2018, time=2018-01-10, status=1, ipAttribution=)]
    2018-01-10 changjiu

    学习一下谢谢

    0

  10. 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