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流感疫苗,可保护心血管病高危或患病人群!Meta分析

2022-08-02 中国循环杂志 网络

根据2019年发表的数据,中国流感疫苗总覆盖率不足2%。

接种流感疫苗对于心血管有保护作用。国内外指南强烈建议心血管病患者每年接种流感疫苗,并将接种流感疫苗作为心血管疾病的二级预防措施之一。

近日,一项纳入18项研究(5项随机对照试验和13项观察性研究)的217072例患者的大型Meta分析进一步证实,心血管高危人群或心血管病患者接种流感疫苗可减少主要不良心血管事件、全因死亡、心血管死亡和心肌梗死风险。

217072例患者中,接种疫苗患者111073例,未接种疫苗患者105999例。平均年龄为68岁。

在平均随访1.5年时,与未接种疫苗患者相比,接种疫苗患者的全因死亡风险降低29%、主要不良心血管事件风险降低17%、心血管死亡风险降低22%,心肌梗死风险降低18%。

两组之间的卒中风险和心力衰竭风险没有差异。

作者指出,这项迄今为止最大的Meta分析结果为流感疫苗对高危心血管人群或心血管病患者的益处提供了强有力的证据。

然而全球流感疫苗接种覆盖率仍不理想。相关数据显示,美国心血管病人群中,流感疫苗接种率为67%,远低于2020年健康人计划设定的90%的国家目标。根据2019年发表的数据,中国流感疫苗总覆盖率不足2%。

来源:Cardioprotective effects of Influenza Vaccination among Patients with Established Cardiovascular Disease or at High Cardiovascular Risk: A Systematic Review and Meta-analysis. Eur J Prev Cardiol. 2022 Jul 20.

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    2023-03-26 guojianrong
  3. [GetPortalCommentsPageByObjectIdResponse(id=1644957, encodeId=0c47164495e87, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Thu Sep 15 02:30:07 CST 2022, time=2022-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888452, encodeId=21c4188845299, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Mar 26 04:30:07 CST 2023, time=2023-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1897044, encodeId=b852189e04403, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sun Oct 02 23:30:07 CST 2022, time=2022-10-02, status=1, ipAttribution=)]
    2022-10-02 一闲

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