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盘点:以下人群应警惕自杀风险

2016-07-08 Mechront 译 MedSci原创

美国药物滥用和精神卫生服务管理局(SAMHSA)的数据显示,从2013到2014年,大约每13个年轻人中就有1人有过自杀的想法。美国疾病控制与预防中心(CDC)也与今年4月份发布新报告称,美国人的自杀率正以惊人的速度增长,在最近15年间飙升了24%,特别是10至14岁的女孩群体的自杀率增长了2倍。大家都知道阿片类药物滥用和酗酒会增加自杀率,但是本文要盘点的是其他与自杀风险。1-Pediatri

美国药物滥用和精神卫生服务管理局(SAMHSA)的数据显示,从2013到2014年,大约每13个年轻人中就有1人有过自杀的想法

美国疾病控制与预防中心(CDC)也与今年4月份发布新报告称,美国人的自杀率正以惊人的速度增长,在最近15年间飙升了24%,特别是10至14岁的女孩群体的自杀率增长了2倍

大家都知道阿片类药物滥用和酗酒会增加自杀率,但是本文要盘点的是其他与自杀风险。

1-Pediatrics:库欣综合征患儿在治疗后自杀的风险增加

美国国家卫生研究院对149例库新综合征患者进行了研究分析后发现,治疗数个月后,9名儿童(约6%)有自杀的念头和愤怒,抑郁,易怒和焦虑的爆发经历。其中,在他们治疗的7个月内, 7名儿童经历了这些症状。另外2人在治疗后至少48个月开始出现症状。

研究表明,库欣综合症的儿童有较高的自杀的风险,并且在疾病成功治愈后还会长期存在抑郁,焦虑等心理健康状况。

2-JCSM:梦魇会让人自杀吗?

英国曼彻斯特大学的研究人员对91名伴有创伤和创伤后应激障碍(PTSD)症状的个体进行研究后发现,经历梦魇和没有经历梦魇的人群相比,自杀行为的风险更高(62% vs  20%)。

研究表明,梦魇可能是自杀的显著标志物,靶向梦魇的自杀干预可能会有效。

3-JAMA Psychiatry:癫痫患者易有反复自杀倾向

英国的研究人员对14059例癫痫患者和56184例对照者进行研究后发现,癫痫组与对照组相比,接受癫痫诊断前首次企图自杀的风险增加了2.9倍(95%CI,2.5-3.4倍)。诊断后癫痫发作的278名患者与对照组相比,反复自杀的风险增加了1.8倍(95%CI,1.3-2.5倍)。

研究表明,企图自杀和反复企图自杀与癫痫有关。

4-Sociology of Health & Illness:出狱犯人自杀风险高于常人8倍,他们也需要关爱

英国普利茅斯半岛医学和牙科医院的研究人员对出狱犯人的研究表明,男性罪犯出狱后的自杀风险是全国平均自杀发生率的八倍。此外,超过1/4的出狱犯人自杀成功发生在释放后的第一个月内。

5-JAMA Psychiatry:警惕!年幼失去父母的孩子自杀风险更高!

研究者对730万人(其中189094名儿童(占2.6%)在18岁之前经历了丧亲之痛)进行研究后发现,经历丧亲之痛后,男孩的自杀风险为4/1000,女孩的自杀风险为2/1000。父母死于自杀的孩子相比父母死于其他方式的民众而言,自杀风险最高。作为父母的第一个孩子、男孩、6岁之前经历丧亲之痛这三大因素都会增加孩子的自杀风险,且后代的自杀风险会增加30%。

6-PLoS One:工作时间过长与自杀观念相关

韩国延世大学医学院的研究者对12076名受试者进行研究后发现,相比于每周工作52小时及以下的个体,每周工作超过60个小时的个体体验到自杀观念的风险高37%;对于男性(OR 1.36,1.09–1.70)及女性(OR 1.38,1.11–1.72)工作者而言,工作时长与自杀观念的相关性相仿,且均具有统计学意义。

研究表明,长时间工作与自杀观念相关,这一点对于男性及女性均是如此。

7-BMJ:抗抑郁药物的使用与自杀风险

研究者对238963名抑郁症患者进行研究后发现,87.7%(n=209,476)的患者接受了至少一次的抗抑郁药物处方。治疗持续时间中位数为221天(四分位范围 79-590天)。在第一个5年随访中,198例自杀,5243例尝试自杀或自身伤害。治疗期间,三环类抗抑郁药物相比SSRI对自杀风险没有统计学差异(aHR 0.84,95%CI 0.47-1.50);其他类别抗抑郁药物使用时,自杀风险显著增加(aHR 2.64,95%CI 1.74-3.99)。米氮平与西酞普兰相比,其明显增加自杀风险(aHR 3.70,95%CI 2.00-6.84)。自杀的绝对风险为0.02%(阿米替林)-0.19%(米氮平)。

三环类抗抑郁药物相比SSRI对尝试自杀或自身伤害没有统计学差异(aHR 0.96,95%CI 0.87-1.08);其他类别抗抑郁药物使用时,尝试自杀或自我伤害显著增加(aHR 1.80,95%CI 1.61-2.00)。与西酞普兰相比,以下三种最常用的药物增加尝试自杀或自我伤害风险:文拉法辛(aHR 1.85,95%CI 1.61-2.13)、曲唑酮(aHR 1.73,95%CI 1.26-2.37)、米氮平(aHR 1.70,95%CI 1.44-2.02),但是阿米替林表现出降低其风险(aHR 0.71,95%CI 0.59-1.85)。尝试自杀或自我伤害的绝对风险为1.02%(阿米替林)-2.96%(文拉法辛)。在开始抗抑郁治疗的28天内其风险最高,在停止治疗的28天内,其风险持续上升。

研究表明,三环类抗抑郁药物与SSRI在自杀和尝试自杀或自我伤害的风险上差别无统计学意义。米氮平、文拉法辛和曲唑酮的使用发生自杀和尝试自杀或自我伤害的风险最高,但是因为自杀例数较少,不足以推断出精确结论。

8-JAMA Psychiatry::晒太阳也能诱发自杀?


维也纳医科大学的研究人员对奥地利近7万个个体的自杀数据进行分析后发现,接受一段时间较少的光线照射后立马进行太阳光照射会影响个体的大脑,这个时候也是个体最脆弱的时候,在这段时间里过多的太阳光照射就会导致个体活动水平的增加,对于抑郁症个体而言,这就可以增加其内心的不安及冲动性行为,最终致使个体产生自杀念头。

研究表明,在好天气(晴天,可以晒太阳的天气)刚开始的头几天里,个体内心的不安(对好天气的期盼)及活动的增加往往会增加其自杀的风险。

研究者也指出,研究者表示,这种现象不光出现在奥地利,在其它国家也是一样的,大多数的自杀往往是在春季发生的,揭示季节和自杀率的关系或许为阐明季节对机体生物学控制的机制提供一定的帮助。

9-JAMA Psychiatry:受失眠困扰的老年人更容易自杀

美国斯坦福大学医学院的研究人员对14456位参与者的研究分析后发现,睡眠较差者比睡眠较好者自杀几率更高,近1.4倍。

研究表明,受失眠困扰的老年人更容易自杀。

10-Psychosom Med:脑卒中患者5年内自杀死亡风险提高10倍

研究者对93027位日本常住居民进行研究后发现,与非卒中人群相比,卒中人群在头5年内自杀的风险上升到10.2倍 (95%CI:6.3-16.6)。

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    2016-10-11 ylzr123

    赞一个!好文章拜读了,认真学习了。

    0

  3. 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level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Wed Aug 03 17:17:00 CST 2016, time=2016-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92802, encodeId=571e9280224, content=唉!生活不易啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160611/IMG575BDDE29B42C3218.jpg, createdBy=5c861626135, createdName=hl573567, createdTime=Tue Jul 12 07:21:00 CST 2016, time=2016-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92673, encodeId=d704926e334, content=额, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sun Jul 10 22:53:00 CST 2016, time=2016-07-10, status=1, ipAttribution=)]
    2016-09-21 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

  4. 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level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Wed Aug 03 17:17:00 CST 2016, time=2016-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92802, encodeId=571e9280224, content=唉!生活不易啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160611/IMG575BDDE29B42C3218.jpg, createdBy=5c861626135, createdName=hl573567, createdTime=Tue Jul 12 07:21:00 CST 2016, time=2016-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92673, encodeId=d704926e334, content=额, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sun Jul 10 22:53:00 CST 2016, time=2016-07-10, status=1, ipAttribution=)]
    2016-09-13 舒心和人

    总结的挺好,感谢分享,认真学习学习

    0

  5. 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level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Wed Aug 03 17:17:00 CST 2016, time=2016-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92802, encodeId=571e9280224, content=唉!生活不易啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160611/IMG575BDDE29B42C3218.jpg, createdBy=5c861626135, createdName=hl573567, createdTime=Tue Jul 12 07:21:00 CST 2016, time=2016-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92673, encodeId=d704926e334, content=额, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sun Jul 10 22:53:00 CST 2016, time=2016-07-10, status=1, ipAttribution=)]
    2016-09-10 ylzr123

    学习了。赞!好文需探究。

    0

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level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Wed Aug 03 17:17:00 CST 2016, time=2016-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92802, encodeId=571e9280224, content=唉!生活不易啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160611/IMG575BDDE29B42C3218.jpg, createdBy=5c861626135, createdName=hl573567, createdTime=Tue Jul 12 07:21:00 CST 2016, time=2016-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92673, encodeId=d704926e334, content=额, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sun Jul 10 22:53:00 CST 2016, time=2016-07-10, status=1, ipAttribution=)]
    2016-08-28 ylzr123

    深度好文,值得学习,赞!

    0

  7. 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level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Wed Aug 03 17:17:00 CST 2016, time=2016-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92802, encodeId=571e9280224, content=唉!生活不易啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160611/IMG575BDDE29B42C3218.jpg, createdBy=5c861626135, createdName=hl573567, createdTime=Tue Jul 12 07:21:00 CST 2016, time=2016-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92673, encodeId=d704926e334, content=额, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sun Jul 10 22:53:00 CST 2016, time=2016-07-10, status=1, ipAttribution=)]
    2016-08-27 ylzr123

    好文,值得学习,赞一个。

    0

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level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Wed Aug 03 17:17:00 CST 2016, time=2016-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92802, encodeId=571e9280224, content=唉!生活不易啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160611/IMG575BDDE29B42C3218.jpg, createdBy=5c861626135, createdName=hl573567, createdTime=Tue Jul 12 07:21:00 CST 2016, time=2016-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92673, encodeId=d704926e334, content=额, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, 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    2016-08-03 oo902

    警惕**

    0

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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sun Jul 10 22:53:00 CST 2016, time=2016-07-10, status=1, ipAttribution=)]
    2016-07-12 hl573567

    唉!生活不易啊!

    0

  10. 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createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Oct 11 22:16:44 CST 2016, time=2016-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=132038, encodeId=c6291320384d, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 21 08:17:00 CST 2016, time=2016-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125705, encodeId=fec4125e05a2, content=总结的挺好,感谢分享,认真学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Tue Sep 13 20:50:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=119580, encodeId=95ef11958085, content=学习了。赞!好文需探究。, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Sep 10 17:09:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106283, encodeId=110b10628361, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sun Aug 28 12:22:00 CST 2016, time=2016-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105726, encodeId=b5ae105e26e4, content=好文,值得学习,赞一个。, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 16:56:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=95768, encodeId=b53495e68ec, content=警惕**, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Wed Aug 03 17:17:00 CST 2016, time=2016-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92802, encodeId=571e9280224, content=唉!生活不易啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160611/IMG575BDDE29B42C3218.jpg, createdBy=5c861626135, createdName=hl573567, createdTime=Tue Jul 12 07:21:00 CST 2016, time=2016-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92673, encodeId=d704926e334, content=额, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Sun Jul 10 22:53:00 CST 2016, time=2016-07-10, status=1, ipAttribution=)]
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