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Psychosom Med:脑卒中患者5年内自杀死亡风险提高10倍

2014-07-25 MedSci MedSci原创

俗称“中风”的脑卒中患者要引起注意了,日本国立癌症研究中心发表研究报告说,脑卒中患者发病后5年内,因自杀和意外事故而死亡的风险相当于普通人的10倍左右。 此前的研究显示,脑卒中发病后1年以内患抑郁症的风险将提高。而这项新研究是首次调查脑卒中与自杀和事故死亡的关系。研究小组从1990年开始,用约20年时间,对日本8个县约9.3万居民的健康状态进 行了跟踪调查。开始调查时,这些居民的年

俗称“中风”的脑卒中患者要引起注意了,日本国立癌症研究中心发表研究报告说,脑卒中患者发病后5年内,因自杀和意外事故而死亡的风险相当于普通人的10倍左右。

此前的研究显示,脑卒中发病后1年以内患抑郁症的风险将提高。而这项新研究是首次调查脑卒中与自杀和事故死亡的关系。研究小组从1990年开始,用约20年时间,对日本8个县约9.3万居民的健康状态进 行了跟踪调查。开始调查时,这些居民的年龄从40岁至69岁不等。调查期间,共有512人自杀,其中有22人患有脑卒中,他们在发病后5年内自杀的危险性 约为未患脑卒中者的10倍。

这项研究从日本公共健康中心的前瞻性数据库中,选择从1990年到2010年,通过Poisson回归模型计算自杀与事故死亡的风险。通过校正不可测量的混杂因素,采用病例交叉分析(case-crossover analyse),研究卒中患者死于自杀和因交通事故、跌落、摔倒等“外在原因”而死亡的风险。

该人群包括93027位日本常住居民,在随访期间,4793位居民被诊断为卒中。其中22位自杀,53位因外在原因死亡死亡;在非卒中人群中,有490位自杀,675位因外在原因死亡。与非卒中人群相比,卒中人群在头5年内自杀的风险上升到10.2倍 (95%CI:6.3-16.6),而因外在原因死亡风险为12.8倍(95%CI:9.0-18.2),进一步通过病例交叉分析确认了这一结果。

脑卒中发病后,往往会留下麻痹和语言障碍等后遗症,患者心理压力非常大,容易导致自杀,而因事故死亡的危险性提高也与后遗症有关。

原始出处:

Yamauchi T, Inagaki M, Yonemoto N, Iwasaki M, Inoue M, Akechi T, Iso H, Tsugane S.Death by suicide and other externally caused injuries after stroke in Japan (1990-2010): the Japan public health center-based prospective study.Psychosom Med. 2014 Jul-Aug;76(6):452-9.

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    2014-07-30 xiaoxifeng

    临床上卒中后抑郁是非常常见的,并且也非常棘手。

    0

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