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Am Heart J:成人酒精摄入量与LVEF呈U型相关

2014-04-16 cath 医学论坛网

美国一项研究表明,成人酒精摄入量与左心室射血分数(LVEF)呈U型相关性,即轻度饮酒者(<1次/天)的中度左心室功能障碍风险最低。该项研究结果与酒精摄入量和心血管疾病发病率的相关性相类似。论文4月7日在线发表于《美国心脏杂志》(Am Heart J)。 该基于人群的研究纳入了2042例年龄≥45岁受试者,利用自我管理的调查问卷评估其酒精摄入量。根据酒精摄入量将其分为5类:戒酒者、既往

美国一项研究表明,成人酒精摄入量与左心室射血分数(LVEF)呈U型相关性,即轻度饮酒者(<1次/天)的中度左心室功能障碍风险最低。该项研究结果与酒精摄入量和心血管疾病发病率的相关性相类似。论文4月7日在线发表于《美国心脏杂志》(Am Heart J)。

该基于人群的研究纳入了2042例年龄≥45岁受试者,利用自我管理的调查问卷评估其酒精摄入量。根据酒精摄入量将其分为5类:戒酒者、既往饮酒者、轻度饮酒者(<1次/天)、中度饮酒者(1—2次/天)和重度饮酒者(>2次/天)。利用超声心动图评估受试者的收缩压。

结果显示,在受试者中确认了38例收缩功能障碍的病例。酒精摄入量与中度收缩功能障碍(LVEF≤40%)呈U型相关;与重度饮酒者相比,轻度饮酒者的发病率最低(0.9%对5.5%,OR值为0.14)。跨越不同阶层收缩功能不全的危险因素和在多变量分析中这种相关性依然存在。在LVEF >50%或≤50%的受试者中,酒精摄入量和收缩功能无显著相关性。

原始出处:


Haroon Yousaf, MD, Richard J. Rodeheffer, MD, Timothy E. Paterick, MD, JD, Zain Ashary, BS, Mirza Nubair Ahmad, MBBS, Khawaja Afzal Ammar, MD.Association between alcohol consumption and systolic ventricular function.Am Heart J April 07 2014. 

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    2015-01-02 lmm397
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    2014-04-18 zhaojie88
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