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J Periodontol:吸烟对非手术治疗牙周炎效果的影响

2020-04-30 网络 网络

吸烟是人类许多疾病的一个重要病因,包括心血管疾病、胃溃疡、胰腺癌、慢性阻塞性肺疾病等,也是牙周炎发生发展的一种重要危险因素。吸烟不仅会提高牙周炎的发病率,加重牙周炎病变的严重程度,也会影响牙周炎的治疗

吸烟是人类许多疾病的一个重要病因,包括心血管疾病、胃溃疡、胰腺癌、慢性阻塞性肺疾病等,也是牙周炎发生发展的一种重要危险因素。吸烟不仅会提高牙周炎的发病率,加重牙周炎病变的严重程度,也会影响牙周炎的治疗效果。本研究旨在评价吸烟对牙周炎患者非手术治疗效果的影响。

实验纳入III期,IV期,C级牙周炎患者,采用传统的牙周非手术治疗法,在治疗结束后的基线、1个月、3个月和6个月进行全口牙周检查。在同一时间点获取唾液、龈沟液、龈下菌斑和血液样本。检测炎症细胞因子水平、11种不同的细菌和数量。并通过烟碱测定法检测患者的吸烟状况。

共有14名吸烟者和13名非吸烟者完整参与实验,除了非吸烟者在6个月时菌斑指数较高外,其他临床研究结果相似(P<0.01)。实验组在1个月和3个月时的生物液中细胞因子水平有显着差异(P<0.01)。基线时,吸烟者的革兰氏阴性菌更丰富,非吸烟者的革兰氏阳性菌更多(P <0.01)。吸烟者中的革兰氏阴性菌比不吸烟者增长快(P <0.01)。

本研究结果表明,吸烟者在6个月的随访中,非手术治疗的III期,IV期,C级牙周炎牙周炎患者反应良好。然而,吸烟者表现出较快的革兰氏阴性菌的再增殖。

原始出处:

Burcu Kanmaz, Effects of smoking on non‐surgical periodontal therapy in patients with periodontitis Stage III or IV, and Grade C. journal of periodontology, 2020, doi:10.1002/JPER.19-0141

 

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    2020-08-24 feather89
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    2020-05-01 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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