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Eur Urol Oncol:非精索瘤患者化疗后残留肿瘤的单侧或双侧腹膜后淋巴结清扫术

2021-03-31 AlexYang MedSci原创

在人群中,非精源生殖细胞瘤和10-49mm残留肿瘤患者的腹膜后淋巴结转移的分布是未知的。而这些信息需要来证明选择患者进行单侧模板切除术的合理性。

在人群中,非精源生殖细胞瘤和10-49mm残留肿瘤患者的腹膜后淋巴结转移的分布是未知的。而这些信息需要来证明选择患者进行单侧模板切除术的合理性。

最近,有研究人员阐述了非精源生殖细胞瘤(NSGCT)患者腹膜后转移和复发的位置, 残留肿瘤为10-49mm

RETROP是一项基于人群的前瞻性观察图谱研究,研究对象为瑞典和挪威的213例腹膜后残留肿瘤为10-49 mm的患者,这些患者在2007-2014年期间因转移性NSGCT接受了化疗后腹膜后淋巴结清扫术,随访时间中位数为100个月。根据睾丸原发肿瘤和化疗前和/或化疗后计算机断层扫描(CT)中出现的单侧或双侧淋巴结转移(参照主动脉)的分布情况对患者进行分类。研究结果表明,共有65%的患者在CT扫描中出现单侧腹膜后淋巴结转移(RLNMs)。单侧RLNMs患者发生对侧畸胎瘤或癌变(右侧NSGCT为1.6%,左侧NSGCT为2.6%)或腹膜后复发(右侧NSGCT为0%,左侧NSGCT为4%)的风险较低。该研究的一个不足之处为部分患者的病理标本不能完全指定到某一特定区域。

PC-RPLND结果

最后,研究人员指出,男性化疗后残余病灶为10-49mm,化疗前和化疗后CT扫描有单侧转移,其对侧病灶风险较低,应考虑进行单侧模板切除

原始出处

Axel Gerdtsson , Anna Thor , Anna Grenabo Bergdahl et al. Unilateral or Bilateral Retroperitoneal Lymph Node Dissection in Nonseminoma Patients with Postchemotherapy Residual Tumour? Results from RETROP, a Population-based Mapping Study by the Swedish Norwegian Testicular Cancer Group. Eur Urol Oncol. Mar 2021

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    2021-07-17 minlingfeng
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    2021-04-02 sodoo
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  7. [GetPortalCommentsPageByObjectIdResponse(id=1866036, encodeId=d70a18660362d, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Sat Jul 17 02:17:07 CST 2021, time=2021-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973354, encodeId=98be19e33547e, content=<a href='/topic/show?id=b7d8660203a' target=_blank style='color:#2F92EE;'>#淋巴结清扫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66020, encryptionId=b7d8660203a, topicName=淋巴结清扫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Thu Nov 25 15:17:07 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1931919, encodeId=59f219319199b, content=<a href='/topic/show?id=6f9885648e1' target=_blank style='color:#2F92EE;'>#腹膜后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85648, encryptionId=6f9885648e1, topicName=腹膜后)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Thu Oct 28 23:17:07 CST 2021, time=2021-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1293122, encodeId=dd6d129312204, content=<a href='/topic/show?id=df626600877' target=_blank style='color:#2F92EE;'>#淋巴结#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66008, encryptionId=df626600877, topicName=淋巴结)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6cc1239, createdName=sodoo, createdTime=Fri Apr 02 11:17:07 CST 2021, time=2021-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522467, encodeId=32fe152246e45, content=<a href='/topic/show?id=46223e39897' target=_blank style='color:#2F92EE;'>#双侧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37398, encryptionId=46223e39897, topicName=双侧)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=741b11453403, createdName=wangbingxhy, createdTime=Fri Apr 02 11:17:07 CST 2021, time=2021-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1590177, encodeId=f0aa15901e729, content=<a href='/topic/show?id=c86e66021c9' target=_blank style='color:#2F92EE;'>#淋巴结清扫术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66021, encryptionId=c86e66021c9, topicName=淋巴结清扫术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3dec17785365, createdName=kord1988, createdTime=Fri Apr 02 11:17:07 CST 2021, time=2021-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623859, encodeId=497e1623859e3, content=<a href='/topic/show?id=16ba8564526' target=_blank style='color:#2F92EE;'>#腹膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85645, encryptionId=16ba8564526, topicName=腹膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93e220615097, createdName=xuyong530, createdTime=Fri Apr 02 11:17:07 CST 2021, time=2021-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=953127, encodeId=b33f95312e50, content=赞赞赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66942067627, createdName=1881ef655dm, createdTime=Thu Apr 01 17:35:38 CST 2021, time=2021-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1038239, encodeId=9b7e10382392d, content=谢谢梅斯分享这么多精彩信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=anti-cancer, createdTime=Wed Mar 31 23:17:07 CST 2021, time=2021-03-31, status=1, ipAttribution=)]
    2021-04-02 xuyong530
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    2021-04-01 1881ef655dm

    赞赞赞

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1866036, encodeId=d70a18660362d, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Sat Jul 17 02:17:07 CST 2021, time=2021-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973354, encodeId=98be19e33547e, content=<a href='/topic/show?id=b7d8660203a' target=_blank style='color:#2F92EE;'>#淋巴结清扫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66020, encryptionId=b7d8660203a, topicName=淋巴结清扫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Thu Nov 25 15:17:07 CST 2021, time=2021-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1931919, encodeId=59f219319199b, content=<a href='/topic/show?id=6f9885648e1' target=_blank style='color:#2F92EE;'>#腹膜后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85648, encryptionId=6f9885648e1, topicName=腹膜后)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Thu Oct 28 23:17:07 CST 2021, time=2021-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1293122, encodeId=dd6d129312204, content=<a href='/topic/show?id=df626600877' target=_blank style='color:#2F92EE;'>#淋巴结#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66008, encryptionId=df626600877, topicName=淋巴结)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6cc1239, createdName=sodoo, createdTime=Fri Apr 02 11:17:07 CST 2021, time=2021-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522467, encodeId=32fe152246e45, content=<a href='/topic/show?id=46223e39897' target=_blank style='color:#2F92EE;'>#双侧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37398, encryptionId=46223e39897, topicName=双侧)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=741b11453403, createdName=wangbingxhy, createdTime=Fri Apr 02 11:17:07 CST 2021, time=2021-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1590177, encodeId=f0aa15901e729, content=<a href='/topic/show?id=c86e66021c9' target=_blank style='color:#2F92EE;'>#淋巴结清扫术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66021, encryptionId=c86e66021c9, topicName=淋巴结清扫术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3dec17785365, createdName=kord1988, createdTime=Fri Apr 02 11:17:07 CST 2021, time=2021-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623859, encodeId=497e1623859e3, content=<a href='/topic/show?id=16ba8564526' target=_blank style='color:#2F92EE;'>#腹膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85645, encryptionId=16ba8564526, topicName=腹膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93e220615097, createdName=xuyong530, createdTime=Fri Apr 02 11:17:07 CST 2021, time=2021-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=953127, encodeId=b33f95312e50, content=赞赞赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66942067627, createdName=1881ef655dm, createdTime=Thu Apr 01 17:35:38 CST 2021, time=2021-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1038239, encodeId=9b7e10382392d, content=谢谢梅斯分享这么多精彩信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=anti-cancer, createdTime=Wed Mar 31 23:17:07 CST 2021, time=2021-03-31, status=1, ipAttribution=)]
    2021-03-31 anti-cancer

    谢谢梅斯分享这么多精彩信息

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