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JAMA Psychiatry:住院感染自杀风险高!

2016-08-18 Seven L 译 MedSci原创

根据最近的调查结果显示,与非感染者相比,有感染的住院病人更容易自杀。来自哥本哈根大学医院的Helene Lund-Sørensen为了评估住院感染和自杀死亡风险之间的关联,进项了一项全国性的以人群为基础的前瞻性队列研究,纳入了1980-2011年居住在丹麦的≥15岁的722万人,随访时间超过1亿4900万人年。随访期间共发生32683例自杀事件。在这些人中,有24.1%的人在住院期间被诊断为感染。

根据最近的调查结果显示,与非感染者相比,有感染的住院病人更容易自杀。

来自哥本哈根大学医院的Helene Lund-Sørensen为了评估住院感染和自杀死亡风险之间的关联,进行了一项全国性的以人群为基础的前瞻性队列研究,纳入了1980-2011年居住在丹麦的≥15岁的722万人,随访时间超过1亿4900万人年。

随访期间共发生32683例自杀事件。在这些人中,有24.1%的人在住院期间被诊断为感染。

数据显示,住院感染与自杀风险的增加有关;与未感染的人相比,发生率比值(IRR)为1.42 (95% CI, 1.38-1.46)。研究者还发现了不同感染和住院天数对医院感染数量的剂量反应关系。≥7个感染的IRR为2.9 (95% CI, 2.14-3.93)。医院治疗持续3个月以上的IRR为2.38 (95% CI, 2.05-2.76)。据研究人员说,住院感染对自杀的人群归因风险为10.1%。

研究人员写道:不管是前瞻性还是剂量反应关系中均观察到了住院感染和自杀风险之间的联系。我们的研究结果表明,感染可能在自杀行为的病理生理机制中有相关的作用。如果感染和自杀死亡风险之间是因果关系,那么识别和早期治疗感染,或许可以作为预防自杀的公共卫生措施。不过事实是否如此,还需要进一步的研究。

原始出处:

Study shows link between infection, increased risk for suicide
.Healio.August 17, 2016

Lund-Sørensen H, et al. A Nationwide Cohort Study of the Association Between Hospitalization With Infection and Risk of Death by Suicide.JAMA Psychiatry. 2016;doi:10.1001/jamapsychiatry.2016.1594.


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createdTime=Fri Aug 19 22:57:00 CST 2016, time=2016-08-19, status=1, ipAttribution=)]
    2016-09-06 李东泽

    很好,不错,以后会多学习

    0

  4. 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GetPortalCommentsPageByObjectIdResponse(id=101222, encodeId=5bc21012228f, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLMzGpMQ8w4I7FpiblCXNcmI6O7TDINutbaicEUpoYFR1rWqn3kTbulfMhT0iaPFurLz2ddEcWe3BiciaQ/0, createdBy=5f6e1724878, createdName=136****0753赵, createdTime=Fri Aug 19 23:03:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=101174, encodeId=e0041011e4f7, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLMzGpMQ8w4I7FpiblCXNcmI6O7TDINutbaicEUpoYFR1rWqn3kTbulfMhT0iaPFurLz2ddEcWe3BiciaQ/0, createdBy=5f6e1724878, createdName=136****0753赵, createdTime=Fri Aug 19 22:57:00 CST 2016, time=2016-08-19, status=1, ipAttribution=)]
    2016-08-26 李东泽

    这篇资讯写的真好,带给我们新知识,启发新思维,不论是科研还是临床工作都有很大的帮助。。。

    0

  5. 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createdTime=Fri Aug 19 22:57:00 CST 2016, time=2016-08-19, status=1, ipAttribution=)]
    2016-08-26 李东泽

    这篇资讯写的真好,带给我们新知识,启发新思维,不论是科研还是临床工作都有很大的帮助。。。

    0

  6. 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GetPortalCommentsPageByObjectIdResponse(id=101222, encodeId=5bc21012228f, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLMzGpMQ8w4I7FpiblCXNcmI6O7TDINutbaicEUpoYFR1rWqn3kTbulfMhT0iaPFurLz2ddEcWe3BiciaQ/0, createdBy=5f6e1724878, createdName=136****0753赵, createdTime=Fri Aug 19 23:03:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=101174, encodeId=e0041011e4f7, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLMzGpMQ8w4I7FpiblCXNcmI6O7TDINutbaicEUpoYFR1rWqn3kTbulfMhT0iaPFurLz2ddEcWe3BiciaQ/0, createdBy=5f6e1724878, createdName=136****0753赵, createdTime=Fri Aug 19 22:57:00 CST 2016, time=2016-08-19, status=1, ipAttribution=)]
    2016-08-21 1e0d99ddm02(暂无匿称)

    **了还是医院的责任,一定要看好病人!!防止医闹!

    0

  7. 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  8. 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    2016-08-19 136****0753赵

    值得学习

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  9. 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    2016-08-19 136****0753赵

    值得学习

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